Protein Info for MIT1002_02163 in Alteromonas macleodii MIT1002

Annotation: Putative oxidoreductase MhqP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 149 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 89 to 110 (22 residues), see Phobius details amino acids 118 to 139 (22 residues), see Phobius details PF07681: DoxX" amino acids 19 to 105 (87 residues), 84.3 bits, see alignment E=7.5e-28 PF04173: DoxD" amino acids 68 to 148 (81 residues), 31.1 bits, see alignment E=2.2e-11

Best Hits

Swiss-Prot: 40% identical to MHQP_BACSU: Putative oxidoreductase MhqP (mhqP) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 87% identity to amc:MADE_02099)

Predicted SEED Role

"Membrane protein, distant similarity to thiosulphate:quinone oxidoreductase DoxD"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (149 amino acids)

>MIT1002_02163 Putative oxidoreductase MhqP (Alteromonas macleodii MIT1002)
MNKQFLKNIFTSNSSISSLVLRVPVGIILTAHGAQKLFAWFGGYGLEGTGQWMESIGLAP
GFLMALLAGSAEFFGGLALIIGFLTRPAALVSAFTMVIAIFSVHAANGLFMTNNGYEFAL
TLLAATGALAIQGGGKFSIDSLISHKLDK