Protein Info for MIT1002_01966 in Alteromonas macleodii MIT1002

Annotation: extracellular lipase, Pla-1/cef family

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 865 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details TIGR03502: extracellular lipase, Pla-1/cef family" amino acids 1 to 850 (850 residues), 801.1 bits, see alignment E=5.5e-245 PF12262: Lipase_bact_N" amino acids 47 to 275 (229 residues), 95.8 bits, see alignment E=1.3e-31

Best Hits

KEGG orthology group: None (inferred from 93% identity to amc:MADE_01894)

Predicted SEED Role

"FIG00951695: hypothetical protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (865 amino acids)

>MIT1002_01966 extracellular lipase, Pla-1/cef family (Alteromonas macleodii MIT1002)
MRKLVLSSSVALALGLAGCGGSDETLSDIQAETEVQTPFSRIVFDPANGNLNIPNDLLML
PGDDGFFDYTLNIPVDDPTDFADPQNALNVLDGWSTQHPFVINVETPAGASLDASTLSSG
VLLFEATLGLDQSDPDCAQVTTPSAGCKLGDQLTFGVDYVLSLADSNTITFVPLKPLKAA
QGYMLVMTTDLKDSSGKSVQGSTTWDSVRQDIDTNPLSSAAQLQLQGLVNSLVNPVLGAG
FDREDITYVSAFTTQSIANSLDTIKKVMISRFAQLAAGGDPSAPTALPAITVSDVSAAPN
AMEALGLVNATVVAGAVEQGKQGLPDNIQAAIDATDFSLLETCAGLAGTASGQLSAQWGA
LNEFAVGVSTGILAQAGPFCAAQRYEGNIALPYFLGVPSAENPLAPVNDFWKAACDSGIV
LAGAPQELLADAEPGPNAAMCSSLGLADVRINGEMLDSARNITKFNPYPQPTGGNMGTET
LDVQVTIPDPAIAGALGFPISMPEAGWPVVILAHGITSQKEDMLAITGTLSLAGIASVAI
DQPLHGSRGFDLNGDGTDELNATTVSATHYMNLASLPTARDNLRQSVSDLLGLRLGLNAV
VDITAAQNVKFDMSRVSIMGVSLGAITGGNFASVANTSMGGDLAALDGMFAVKQASLESP
GGGVAQFLIESAAFGPLIKGLLLSQASEEFVALLNQLYETTDVSEEQLRAAVAIFEENLT
AEQAAEVNAVFAEFAFAAQTVMDAGDPTNYAQTLGSNTPVHMMTVVGDGSDANLPDQVIP
ISTALPLSGQLPLAATIGLEQVTTTQGPGTDPISGIVQFNSGAHASSLSPAASAAVTTEM
QKEVAGYIASDALVLPISDESVVAN