Protein Info for MIT1002_01940 in Alteromonas macleodii MIT1002

Annotation: Phosphomannomutase/phosphoglucomutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02878: PGM_PMM_I
  • amino acids 8 to 134 (127 residues), 116.3 bits, E=1.7e-37
• PF02879: PGM_PMM_II
  • amino acids 183 to 287 (105 residues), 78.1 bits, E=1.4e-25
• PF02880: PGM_PMM_III
  • amino acids 292 to 401 (110 residues), 90.2 bits, E=2.1e-29
• PF00408: PGM_PMM_IV
  • amino acids 407 to 477 (71 residues), 35.1 bits, E=2.3e-12

Best Hits

KEGG orthology group: K01840, phosphomannomutase [EC: 5.4.2.8] (inferred from 95% identity to amc:MADE_01868)

Predicted SEED Role

"Phosphomannomutase (EC 5.4.2.8)" in subsystem Alginate metabolism or Mannose Metabolism (EC 5.4.2.8)

MetaCyc Pathways

• GDP-mannose biosynthesis (4/4 steps found)
• colanic acid building blocks biosynthesis (8/11 steps found)
• β-1,4-D-mannosyl-N-acetyl-D-glucosamine degradation (2/3 steps found)
• β-(1,4)-mannan degradation (2/7 steps found)
• superpathway of GDP-mannose-derived O-antigen building blocks biosynthesis (6/14 steps found)

KEGG Metabolic Maps

• Fructose and mannose metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.4.2.8

Protein Sequence (486 amino acids)

>MIT1002_01940 Phosphomannomutase/phosphoglucomutase (Alteromonas macleodii MIT1002)
MATPITCFKAYDIRGELNSQLTEDVAYRIGYAFAQELSAKTVVVGSDVRLTSTPLKLALS
AGLIDAGATVTDIGMAGTEEIYFATKHLGVDGGIEVTASHNPINYNGMKLVKSGSVPISG
DTGLNAIKEKAEALEDSFVSERLAHYTEGALIDADAFFNGTAHVKEDKLSETDKYAVKSC
MSDYVSHMLSYVNLSNFTPLKVVVNAGNGAAGPALDAIEKEMKVQGVPIEFVKVHHNANG
TFPNGIPNPLLPENRADTADAVKASGADFGIAWDGDFDRCFLFDADGEFIEGYYIVGLLA
EAFIEKNTDSKIIYDPRVYWNTEDIVANAGGTPIKSKTGHAFIKERMRKEDAVYGGEMSA
HHYFRDFAYCDSGMIPWLLIAELVCVKKQTLASMVKARIEAFPSSGEINSKLKDADAALE
RVTSKYQPLASVIDTTDGLGLEFGTWRFNLRKSNTEPVIRLNVESKGDIALMEQKTEELL
SLIRAE