Protein Info for MIT1002_01697 in Alteromonas macleodii MIT1002

Annotation: putative membrane protein YjcC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 517 transmembrane" amino acids 18 to 40 (23 residues), see Phobius details amino acids 243 to 265 (23 residues), see Phobius details PF12792: CSS-motif" amino acids 42 to 222 (181 residues), 79.1 bits, see alignment E=3.3e-26 PF00563: EAL" amino acids 274 to 503 (230 residues), 171.9 bits, see alignment E=1.5e-54

Best Hits

Predicted SEED Role

"diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s)" in subsystem Bacterial hemoglobins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (517 amino acids)

>MIT1002_01697 putative membrane protein YjcC (Alteromonas macleodii MIT1002)
MNKSDQKQYFLADNVKAIGVSLLSVVGVTLLLAIVMFVFIREQEESRATEILDNVRVVFR
DAEITLDYLNALPYQTCGMDNLAEMRKTLFRSRFVKEIGFYQNNELLCSTYLDILEEPMK
EVKPDFYTQLGDAFWINTPLQLFDKQATGTIVQRGRYNAVLDMDSVIGYSYTQDWQLFYN
GDQFYHMAGNPSLVGSTLSEDDMDAHTGYFSLQFIQCDERYNHTCLKVKSDHGRVLDLHM
GKLVLFVFAMIMTAALTHMLTFNYLRRRRSLESRVSKGLKEHKFYCLYQPFVNLESGKVI
GCEVLSRFEDEFGPIYPDKFIPQVKEQDMTWEFTVDMITTAMRELNENPETPEGFKVSFN
LFPFDFTREGCLDLDFVLDMNVKNFKLVLEITEDEQIATHSAVKHIKSLKSKGFLFAIDD
FGVGYSNLSQLKTLNCDYLKIDRSFVMDMEDNSIRSSLIPHIVSIAEGLNIDLIAEGVEN
IDQCNELKGLTIGFGQGWLFGKPQSVDALAKSVQGIQ