Protein Info for MIT1002_01588 in Alteromonas macleodii MIT1002

Annotation: Xanthine permease XanP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 525 transmembrane" amino acids 24 to 46 (23 residues), see Phobius details amino acids 53 to 70 (18 residues), see Phobius details amino acids 82 to 101 (20 residues), see Phobius details amino acids 113 to 135 (23 residues), see Phobius details amino acids 142 to 163 (22 residues), see Phobius details amino acids 175 to 194 (20 residues), see Phobius details amino acids 201 to 220 (20 residues), see Phobius details amino acids 240 to 261 (22 residues), see Phobius details amino acids 332 to 354 (23 residues), see Phobius details amino acids 361 to 381 (21 residues), see Phobius details amino acids 390 to 410 (21 residues), see Phobius details amino acids 419 to 439 (21 residues), see Phobius details TIGR00801: uracil-xanthine permease" amino acids 18 to 437 (420 residues), 333.3 bits, see alignment E=1.2e-103 PF00860: Xan_ur_permease" amino acids 22 to 408 (387 residues), 269.5 bits, see alignment E=2.1e-84

Best Hits

KEGG orthology group: K03458, nucleobase:cation symporter-2, NCS2 family (inferred from 91% identity to amc:MADE_02501)

Predicted SEED Role

"Xanthine permease" in subsystem Purine Utilization

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (525 amino acids)

>MIT1002_01588 Xanthine permease XanP (Alteromonas macleodii MIT1002)
MSSNHSELLYDLHDSPAFLPSLTAAFQHLLASFVGVITPTLIVTSTLGLTEYTPYLISMA
LFVSGLGTAIQTKRIGPVGSGLVAIQGTSFAFISALILAGNQVEADGGTPEDVLSLLFGL
TMAGAMVEVVFSLFVHKLKRIITPLTTGIVITAIGLSLINVGMTDLAGGFHAADFASTEN
LAVGLGVLLIIVFLNASTNHWLRLSAIFIGMAIGATYVGITKGLDFSGLASLSVVAIPTP
FAFGIAFDITLFLPIALIYLFSAIETAGDLTANSLFCKQPVSGPIYLARVKGGILGDGVN
SLLAGMFNTFPNTTFGQNNGVIQLTGIASRKVGFFVAALFVVIGFFPIVGGVLQAIPKPV
LGGATLVMFAMVAVGGLKLLASYALDRRSSLVTACALGMAIGVMMVPEALSELPSWLENI
LLSPVTSAGLTAVILDLTLPGKKPLASPHASAQKIESSTGVAQDNPAYEPIHNPKPEGNR
RAPKALNEKAVVNHEVVKHSAHSTHILSIDGQPGVTSALFSAKAR