Protein Info for MIT1002_01417 in Alteromonas macleodii MIT1002

Annotation: Epimerase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 PF04321: RmlD_sub_bind" amino acids 1 to 237 (237 residues), 29.5 bits, see alignment E=6.1e-11 PF01370: Epimerase" amino acids 3 to 221 (219 residues), 66.2 bits, see alignment E=4.6e-22 TIGR01777: TIGR01777 family protein" amino acids 3 to 292 (290 residues), 354.5 bits, see alignment E=2.8e-110 PF08338: DUF1731" amino acids 249 to 294 (46 residues), 63.4 bits, see alignment 1.9e-21

Best Hits

Swiss-Prot: 53% identical to YFCH_ECOLI: Epimerase family protein YfcH (yfcH) from Escherichia coli (strain K12)

KEGG orthology group: K07071, (no description) (inferred from 74% identity to amc:MADE_02301)

Predicted SEED Role

"Cell division inhibitor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>MIT1002_01417 Epimerase family protein (Alteromonas macleodii MIT1002)
MNILLTGGTGLIGSEFIRQYSREHEFTVISRDFAKAKSKLGDNVKIVENVSSLENFESFD
AVINLAGEPIADKRWTDTQKKIICNSRWDITSELVSKINSCDAPPSVFLSGSAIGYYGNQ
GDKLVTEETPPHNEFTHELCAKWETIAQSVDQAKTRVVTLRTGVVFTEKGGALGKMALPF
KLGAGGTLGSGSQYLAWIHLQDMVRAISFLLENSACSGAFNLTAPEPVTNKMFSKALAKS
LNRPCLFNVPGFVMKVAMGESSTMILEGQRVIPQKLTTAGFSFDFRSIDEALREMYRA