Protein Info for MIT1002_01161 in Alteromonas macleodii MIT1002

Annotation: tetratricopeptide repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 594 PF13432: TPR_16" amino acids 44 to 101 (58 residues), 16.6 bits, see alignment 6.9e-06 amino acids 73 to 134 (62 residues), 28.9 bits, see alignment E=9.3e-10 amino acids 106 to 169 (64 residues), 15.6 bits, see alignment E=1.4e-05 PF13181: TPR_8" amino acids 72 to 101 (30 residues), 18.5 bits, see alignment (E = 1.3e-06) amino acids 172 to 198 (27 residues), 17 bits, see alignment (E = 4e-06) PF14559: TPR_19" amino acids 84 to 135 (52 residues), 29.9 bits, see alignment 4.4e-10 PF13431: TPR_17" amino acids 91 to 122 (32 residues), 23.2 bits, see alignment (E = 4.4e-08) PF13176: TPR_7" amino acids 172 to 202 (31 residues), 21.9 bits, see alignment (E = 1e-07) PF13759: 2OG-FeII_Oxy_5" amino acids 496 to 588 (93 residues), 88 bits, see alignment E=3.8e-28

Best Hits

Predicted SEED Role

"TPR domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (594 amino acids)

>MIT1002_01161 tetratricopeptide repeat protein (Alteromonas macleodii MIT1002)
MNIVQQLVSAYNQKQYQQIIQFIEKQLFLLQKDPVFIQLFCGSLRQVQRVKEAEKYLVKG
LKKFKNHPELSNALGNLYLSTRRIDLAVSTFQKASELAPNNVDLHYNLARALIEKNALKQ
ARIAAEKVLALVPNHVQTKLILADIFSKQSDFNEAIIVLKDVLAISPENIVALNNIANLY
RKIEDYEQALKHFELALSKTNANPTILRNYAAVLALSNQRERAEMVYLKALKVAPSDWEL
QEELAKFLWEEGVDAPFVHIESYIKRQPEDDSFRFRFIQLLIQADEYHAAKEQLDLLTTE
AIKTHEIAPLRARVLRELGEYEASIVEIEIAKIQSNKVALLSEKGYSLLCLGRAKEALNC
FNQLIKIEPLNQGWWTMLSTCWSMAEQENRYKWLCDYDKLVYVNAIKPSPVDTANFNEKL
KNALVEKHQNQRHPIGQSLKNGTQTYEDLFVTSLPIIKELSENILAQAKLFTAQQCSDKT
HPFLSRLSDKLKYIGSWSVRLKNGGFHKSHYHPEGWLSGVYYVDVPKAVNTDGQGWLMFG
RADIANQRFEGDYAVKPEGGTVVLFPSYMWHGTNAFTTDEHRLTVAFDIIPNEN