Protein Info for MIT1002_00957 in Alteromonas macleodii MIT1002

Annotation: ABC-type transport system involved in multi-copper enzyme maturation, permease component

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 398 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 189 to 211 (23 residues), see Phobius details amino acids 233 to 261 (29 residues), see Phobius details amino acids 280 to 305 (26 residues), see Phobius details amino acids 317 to 337 (21 residues), see Phobius details amino acids 365 to 390 (26 residues), see Phobius details PF12679: ABC2_membrane_2" amino acids 2 to 339 (338 residues), 106.4 bits, see alignment E=3.5e-34 PF12698: ABC2_membrane_3" amino acids 16 to 387 (372 residues), 109.9 bits, see alignment E=3e-35 PF01061: ABC2_membrane" amino acids 167 to 327 (161 residues), 29.3 bits, see alignment E=1.2e-10 PF12730: ABC2_membrane_4" amino acids 193 to 297 (105 residues), 30.3 bits, see alignment E=7.9e-11

Best Hits

KEGG orthology group: K09696, sodium transport system permease protein (inferred from 97% identity to amc:MADE_03077)

Predicted SEED Role

"catalyses ATP-dependent electrogenic Na+ extrusion without mechanistically coupled H+ or K+ uptake"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (398 amino acids)

>MIT1002_00957 ABC-type transport system involved in multi-copper enzyme maturation, permease component (Alteromonas macleodii MIT1002)
MWLIFKKEFKELLRDKKTIIFMIGLPLLLFPAIFGVAFFFMSSAADKAENKILKYAIVGE
AYAPAIVQSFNDASDKFESVAIGDETDYAKLIKNETLDFVLVIPETFDSDVLRSGQHNIE
LYLNDAGLNKVMGRVSDIIDEYTDAFQQTAFAQLNLDETQQEALLKPIKIEKQNVADDRE
VWGERLGGMLPYFIFILCLQGAMAPAADLGAGEKERGTLETLLISPMDRHKLVLGKFFTI
ATAGIITALITVSSMAIWGLVLSQGMAVEFVVKIMSMIGLVDFLLIFLMLVPVVAVFAAI
LLSLSIYARSFKEAQSYMGSLIMVVIFPVIIAMMPGVELKGGWVWVPLTNVALAMKELFK
GTMDYFALFGIFTSTAVIATGLIFFCIHWFNKEKVLFR