Protein Info for MIT1002_00898 in Alteromonas macleodii MIT1002

Annotation: Nuclease SbcCD subunit C

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1245 PF13476: AAA_23" amino acids 6 to 231 (226 residues), 91.5 bits, see alignment E=1.8e-29 PF13558: SbcC_Walker_B" amino acids 1136 to 1199 (64 residues), 45.8 bits, see alignment 9.2e-16

Best Hits

KEGG orthology group: K03546, exonuclease SbcC (inferred from 82% identity to amc:MADE_03135)

Predicted SEED Role

"Exonuclease SbcC" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1245 amino acids)

>MIT1002_00898 Nuclease SbcCD subunit C (Alteromonas macleodii MIT1002)
MRILTLRLKNLNALKGEWKIDFTQSPFIDNGLFAITGPTGAGKTTLLDAICLALYHQTPR
LGPISTSNNDIMTRGTAECLAEVEFDIKGKAYRAFWSMRRARGKVDGNLQSADVELAEVE
SGKVLATQVRPKSEEIEKLAGLNFARFTKSMMLSQGDFAAFLNANEADRAELLEELTGTE
IYGQISQAVHQQFSDAKQKKKEFAIKLEGVTLLSDEQITQLEEEQAQTKSQVATSNQTLV
QLQKQQQWQQAFNANELTIKEASEAQQTANNAINEARQELDLLTQSEPAEKLRLPFLQRN
GLQQDVTRYKERLDEKAAQLPDLKTQKAQRSSEVTHAEQALVLTKQQSRELEKRINEQVV
PLDNQIAQLTTEQQKANENAARLRQSINALTLKRTEIENASADNKTKLGELETYLREHHS
LSGIAEFISGWSETARHIEHDKKQLETLTQSVNNHRQALSSLDDAIAKTNESLSALTQTL
DDKNAQVAKCEKALQAALSDKPSDTNSANATSKASLQQERDTKLHHWDNVLQIGHIQQQY
LALEQEKVSLGAQKEDLAKKLAQQQSDRQALVDAYKQTRSNLKDIEALIALDAEVAHLRA
QLKSGEPCPVCGANEHTTSTVVIDVPETIQKRDSLKQQLDDIEQQGARAKESVTQTEFTL
AQVNKQLEQASGQRDTLLEKWQQISSVLSADIPSFEKVDINTSQSVSQFTQQFKTRLDDI
SAQLTRLEECEQALNAALQAKNEAQQALQGKQSELAVSLQQRETLEKQFNERNTELESKT
KRVNDGILALSETMTAHGADIHNLAIDGIATWLNEKAEALKAYKHNHQLHAKLKDELQGV
SSTLLVVNRDIESAENQLKGVCEELVQLDNSLKALRDSRSTVFPEGNIAETRNKASAAQE
HAERNVNECKSRLQQTDTILSRLEAEIAQLNEQMREKEQALSEATEHFSRQLASSPFADE
HAFSNALLDEDTRNTLLELQKRLTQQKQQADLKLENAIATEQSLKAHANAAQWQSELEEH
GAQWLDSKITQQAQQRDTLLSSLGQIEQQLSANNQARERQQQLVDEMAAFEAYYDDITYL
HSLIGSASGDKFRRFAQGLTLDNLVQLANQQLDKLHGRYQLIRKENEGLGLSVLDTWQGD
VVRDTKTLSGGESFLVSLALALALSDLVSHKTSIDSLFLDEGFGTLDAETLDVALDALDN
LNASGKMIGVISHIEAMKERIPTQLKVIKRNGVGLSALEKPYAVG