Protein Info for MIT1002_00888 in Alteromonas macleodii MIT1002

Annotation: Organic hydroperoxide resistance transcriptional regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 147 PF12802: MarR_2" amino acids 34 to 91 (58 residues), 45.1 bits, see alignment E=2.3e-15 PF01047: MarR" amino acids 35 to 92 (58 residues), 48.8 bits, see alignment E=1.3e-16 PF13601: HTH_34" amino acids 43 to 104 (62 residues), 29.2 bits, see alignment E=2.1e-10 PF13412: HTH_24" amino acids 45 to 81 (37 residues), 22.8 bits, see alignment E=1.3e-08 PF13463: HTH_27" amino acids 49 to 101 (53 residues), 26.4 bits, see alignment E=1.7e-09

Best Hits

Swiss-Prot: 34% identical to SARZ_STAS1: HTH-type transcriptional regulator SarZ (sarZ) from Staphylococcus saprophyticus subsp. saprophyticus (strain ATCC 15305 / DSM 20229)

KEGG orthology group: None (inferred from 84% identity to amc:MADE_03142)

Predicted SEED Role

"Organic hydroperoxide resistance transcriptional regulator" in subsystem Oxidative stress

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (147 amino acids)

>MIT1002_00888 Organic hydroperoxide resistance transcriptional regulator (Alteromonas macleodii MIT1002)
MSELLKLENQLCHRFYTLSNAFTRAYRPLLKALDITYPQYVTLMALWENDGITIAELLER
TAIDGGAMSLILKKLQDKGFLVVTKDKADKRVKRVQLTETGKKEKAIAEDVPVQMLCKLN
GMTADESRTLKVLLDKLGGCFENADLN