Protein Info for MIT1002_00833 in Alteromonas macleodii MIT1002

Annotation: Inner membrane protein YrbG

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 37 to 60 (24 residues), see Phobius details amino acids 72 to 93 (22 residues), see Phobius details amino acids 105 to 122 (18 residues), see Phobius details amino acids 129 to 148 (20 residues), see Phobius details amino acids 173 to 192 (20 residues), see Phobius details amino acids 204 to 228 (25 residues), see Phobius details amino acids 241 to 263 (23 residues), see Phobius details amino acids 274 to 293 (20 residues), see Phobius details amino acids 299 to 317 (19 residues), see Phobius details TIGR00367: K+-dependent Na+/Ca+ exchanger homolog" amino acids 2 to 312 (311 residues), 268.1 bits, see alignment E=4.9e-84 PF01699: Na_Ca_ex" amino acids 5 to 143 (139 residues), 116.9 bits, see alignment E=3.9e-38 amino acids 173 to 317 (145 residues), 127.6 bits, see alignment E=2.1e-41

Best Hits

Swiss-Prot: 56% identical to CAXA_ALKAM: Putative antiporter CaxA (caxA) from Alkalimonas amylolytica

KEGG orthology group: K07301, inner membrane protein (inferred from 97% identity to amc:MADE_03187)

Predicted SEED Role

"Inner membrane protein YrbG, predicted calcium/sodium:proton antiporter"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (318 amino acids)

>MIT1002_00833 Inner membrane protein YrbG (Alteromonas macleodii MIT1002)
MLLNIVIFLVGLIVLSWSADRFVYGASALAKNIGISPMMIGLTIVAMGSSAPEIVVSAIA
SANGNMNTAVGNALGSNITNIALVLGITALVKPLLVSSTTLKRELPALLIISLIAIGFMF
DGELKSYEGIILLGLFIFVLAMMAWLSLQVDKEDPLVAETADEIPKGVSNTSALIWIGVG
LVILPLSAHFLVNSAVEIARYMGISDLVIGLTIIAFGTSLPELAASVAGVLKGEDDLALG
NIIGSNIFNLLAVLGMPGLIAPGILDPDVYNRDMYVMLGLTLLLFLFSFDLIGKRTISRT
NGFILLACFIGYQFWLFG