Protein Info for MIT1002_00745 in Alteromonas macleodii MIT1002

Annotation: Peptidase family M49

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 564 signal peptide" amino acids 1 to 29 (29 residues), see Phobius details PF03571: Peptidase_M49" amino acids 185 to 394 (210 residues), 49.7 bits, see alignment E=1e-17

Best Hits

KEGG orthology group: None (inferred from 94% identity to amc:MADE_03446)

Predicted SEED Role

"Nudix hydrolase 3 (EC 3.6.1.-)" (EC 3.6.1.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.6.1.-

Use Curated BLAST to search for 3.6.1.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (564 amino acids)

>MIT1002_00745 Peptidase family M49 (Alteromonas macleodii MIT1002)
MKKTITTYSPIAAAVAGLFMLTACSKNADTTPTQTAKPETASEQTLLVDESRLSIYHGVD
LTSDLSHLSDNQHKMLSLLIDASKIMDDLFWKQAFFEDKDAFLSSISDEKVRHFAAINYG
PWDRLNGDTPFLSGYEDKSLGAEFYPHDMEKEEFATADFGDKQGLYSMVKRDEAGNLYSV
PYSEAFKSELMKASDLLKKASELAEDESFKQYLQLRSEALLSNDYLASDMAWMDMKTNPV
ELVIGPIESYEDQLFGYRAAFEAYVLIKDLAWSEKLAKYAAFLPELQQGLPVAKAYKAEM
PGSDADLNAYDVIYYAGHSNAGSKTIAINLPNDERVQLEKGTRRLQLKNAMRAKFDTILV
PIADTLIVPEQREHITFDAFFANTMFHEVAHGLGIKNTLDGSGTVRGALKEHASALEEGK
ADILGLYMVQSLLEKGEITEGTLEDYYVTFMAGIFRSVRFGASSAHGKANMIRFNFFAQQ
GAFEKTEDGMYRVNMEKMGAAVEALSELILTLQGDGDYDGVAKLVETMGVIKPDLASDLA
RLEAASIPVDIHFNQGKKVLGLAN