Protein Info for MIT1002_00690 in Alteromonas macleodii MIT1002

Annotation: alpha-ketoglutarate-dependent dioxygenase AlkB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 213 PF13532: 2OG-FeII_Oxy_2" amino acids 25 to 206 (182 residues), 131.3 bits, see alignment E=2.6e-42

Best Hits

KEGG orthology group: None (inferred from 82% identity to amc:MADE_03669)

Predicted SEED Role

"Alkylated DNA repair protein AlkB" in subsystem DNA repair, bacterial

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (213 amino acids)

>MIT1002_00690 alpha-ketoglutarate-dependent dioxygenase AlkB (Alteromonas macleodii MIT1002)
MQFSLFETTENNSSSHKLPLSEGDVTYFPQALSKDDADTFFELLKAELPWRQDSIRLFGK
PVKIPRLQSWHGNDDCTYTYSNLTMSPNPWTNSLLSIKDCCEALCAPTQNTKFNSVLANW
YRDGQDSMSFHSDDEPELGINPVIASVTLGEARPFVFKHKETKEKYTQVLEHGSVLIMAG
TTQSHYVHGIAKTAKPIGGRINLTFRHLIHRTR