Protein Info for MIT1002_00519 in Alteromonas macleodii MIT1002

Annotation: Autoinducer 2 sensor kinase/phosphatase LuxQ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 938 signal peptide" amino acids 1 to 31 (31 residues), see Phobius details transmembrane" amino acids 40 to 71 (32 residues), see Phobius details amino acids 79 to 96 (18 residues), see Phobius details amino acids 102 to 121 (20 residues), see Phobius details amino acids 133 to 158 (26 residues), see Phobius details amino acids 177 to 201 (25 residues), see Phobius details amino acids 449 to 472 (24 residues), see Phobius details PF00512: HisKA" amino acids 575 to 640 (66 residues), 61.8 bits, see alignment 8e-21 PF02518: HATPase_c" amino acids 688 to 797 (110 residues), 104.6 bits, see alignment E=6.2e-34 PF00072: Response_reg" amino acids 819 to 930 (112 residues), 78.7 bits, see alignment E=5.5e-26

Best Hits

KEGG orthology group: None (inferred from 79% identity to amc:MADE_00572)

Predicted SEED Role

"Signal transduction histidine kinase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (938 amino acids)

>MIT1002_00519 Autoinducer 2 sensor kinase/phosphatase LuxQ (Alteromonas macleodii MIT1002)
MKIGSISFSFSWSLALQALLVCVLGAGLNALNPPFDSTGIATFGIGAAVYASLRFSPFIS
IPIALVVSLPLWLNDGSIVGKESLTLLPIVLSFFGYNKSLKQVIKVGAGFWSIVFLPILV
LEHSLYDGDNANMLFSGVLVTWVSGVFGLVTGHFSYLAVHGLKRQTSSKSERVTLHFLFG
YFFSGCFFVASMAVIYLSVSLFQQQQEKQIHSYMSQRVNVLEFQLSNFIQQHQSAIISAA
QVLSSEVSNSDFDNAAVTNLRVLASHNPEFLTFLIADDNGDLTHAYPPSLLDKARQSGLS
NVAYRPYFFEVMQTGKPFLSNVFQGRGFGNDPIVALSAPITDADGTPKGIVEGSLSLKSF
SAIDNLSLGGFLMLIEDQKGEVIYASKGLKMKPLTKAPFYICEPNCAVEVENGPQGKTWL
RLAKDMPFASWKVSYYFDKRLLMASMSNYLLKDLLLLLALSAFGTFTGYVVAKMVGAPIR
RLVRYIAEFDPTQKEVIKAPQRALHIQELSSLSDEFVSLEARLLDAFEELKVAREVEQSL
NVELGELNQSLEKRIEEKTEHLALALKEAEAANVAKTQFLANMSHEIRTPMNGIIGSCEL
MLENELPENVSARAKTISRSASNLLIILDSILDWSKIESGKMLTDIQSCAIRELLEASCD
LYRHAAQVKGYDIALYINQGVPNALNIDAGKVSQIINNLLSNAIKFTSDGVVTVNVSYAH
QGLKISVTDTGIGIAPNKLRLIFDKFEQADPSTTRNFGGTGLGLAISKGLVELLGGELYV
ESELGKGTSFTFHIPATVSEEKEHAENEVIPSLPDGLRVLLAEDNDINAEIVMDMLKSSN
IKCIRTKNGQDAVKAEKRHDFDVILMDCQMPIMDGHTASKLIRSEGRNKDTVRIIALTAN
AFIEDKNACLEAGMNAHLSKPIRKQVLFDCIARELARV