Protein Info for MIT1002_00511 in Alteromonas macleodii MIT1002

Annotation: Bacteriophytochrome cph2

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 632 transmembrane" amino acids 12 to 33 (22 residues), see Phobius details amino acids 192 to 213 (22 residues), see Phobius details amino acids 220 to 243 (24 residues), see Phobius details amino acids 254 to 276 (23 residues), see Phobius details amino acids 288 to 308 (21 residues), see Phobius details amino acids 314 to 334 (21 residues), see Phobius details amino acids 340 to 360 (21 residues), see Phobius details amino acids 374 to 395 (22 residues), see Phobius details PF07696: 7TMR-DISMED2" amino acids 46 to 179 (134 residues), 82.2 bits, see alignment E=5.3e-27 PF07695: 7TMR-DISM_7TM" amino acids 191 to 392 (202 residues), 134.2 bits, see alignment E=9.4e-43 TIGR00254: diguanylate cyclase (GGDEF) domain" amino acids 459 to 624 (166 residues), 163.5 bits, see alignment E=1.8e-52 PF00990: GGDEF" amino acids 464 to 621 (158 residues), 153.2 bits, see alignment E=7.8e-49

Best Hits

KEGG orthology group: None (inferred from 81% identity to amc:MADE_00565)

Predicted SEED Role

"GGDEF domain protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (632 amino acids)

>MIT1002_00511 Bacteriophytochrome cph2 (Alteromonas macleodii MIT1002)
MQTNLKAMRKYDAGLILITLVAVVAFVSVLFNLSPNTSATPRFSQLTYLNVDNGNALDFT
TITQTPLTDWTPIASPINLGMNTNVHWFSMVIAPTQSNESRFLLHIDYPLLDSLDVAIYS
QIGSTPIATYSGGDGLHFDNRPVSHVKPLFPLPVSAQSQRVIIRVQTSGSVRLPIRIWEE
TEFIAYTSSRNLALGIFFGILVAMGVSNAFLTVTTSNVSFLYYSGYVMSLALILATLHGY
GFSYMWPGSTWFQGKAILVFANATIMFAAMFTRSLLPIRAHSVKLDKITQAISWVCGLSI
ILGLILPYSFMIKAFLLLLSLIVIFTLGLGIWLTLKGVVVARYFTIAWGFLLISGLSASL
DNVNIIQLPISSNNLLIIGGAVETLILALILAINYSHSRDDLIEAQQFALEQEKQANTAK
ENLLEVQKRYQDDLEYKVQERTLELEITLRELSEVNQELERLNAIDPLTGAHNRRHFDKR
LRSEGRRSRREQTPLSLIIVDVDHFKQINDQHGHDGGDACLIHVTNVFQKHIHRPTDDLC
RIGGEEFAIILPNTDLEGAFHVAEIMRDSLASTPLDYEGETIKLTASAGVSTTIIIDEEH
AQNLFKFADECLYEAKAAGRNTVIHKHLQEKL