Protein Info for MIT1002_00412 in Alteromonas macleodii MIT1002

Annotation: Inner membrane protein YedI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 307 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details transmembrane" amino acids 73 to 100 (28 residues), see Phobius details amino acids 149 to 167 (19 residues), see Phobius details amino acids 174 to 195 (22 residues), see Phobius details amino acids 223 to 257 (35 residues), see Phobius details amino acids 274 to 299 (26 residues), see Phobius details PF05661: DUF808" amino acids 5 to 294 (290 residues), 348.9 bits, see alignment E=1.1e-108

Best Hits

Swiss-Prot: 57% identical to YEDI_ECOLI: Inner membrane protein YedI (yedI) from Escherichia coli (strain K12)

KEGG orthology group: K09781, hypothetical protein (inferred from 92% identity to amc:MADE_00476)

Predicted SEED Role

"Membrane protein, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (307 amino acids)

>MIT1002_00412 Inner membrane protein YedI (Alteromonas macleodii MIT1002)
MAAANLLALLDDIATLMDDIATMSKVAAQKTAGVLGDDLAVNADQVQGVKADRELPVVWA
VAKGSLINKAILVPAALAISAFVPSLITVLLVLGGLYLCFEGAEKLLHKYLPHEDEEKTR
EARIEALTHEDVDMVAFEKDKIKGAIRTDFILSAEIIVIALGTVTDATLTTQIGVLVALS
LAITLGVYGLVAALVKMDDVGLYMLRKSLTGSMNTLQRFIGRALLVAAPALMKTLAVVGT
VAMFLVGGGILTHSIGFLHVITDWFTALIPDASLVMSILADGVVGIAAGVIIALVVTMVS
QFRSKAS