Protein Info for MIT1002_00353 in Alteromonas macleodii MIT1002

Annotation: Cytoplasmic trehalase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01204: Trehalase
  • amino acids 27 to 503 (477 residues), 431.9 bits, E=4e-133

Best Hits

KEGG orthology group: K01194, alpha,alpha-trehalase [EC: 3.2.1.28] (inferred from 61% identity to alt:ambt_16680)

Predicted SEED Role

"Trehalase (EC 3.2.1.28)" in subsystem Trehalose Uptake and Utilization (EC 3.2.1.28)

MetaCyc Pathways

• trehalose degradation II (cytosolic) (2/2 steps found)
• trehalose degradation VI (periplasmic) (2/2 steps found)
• chitin biosynthesis (6/9 steps found)

KEGG Metabolic Maps

• Starch and sucrose metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.2.1.28

Protein Sequence (507 amino acids)

>MIT1002_00353 Cytoplasmic trehalase (Alteromonas macleodii MIT1002)
MSSSSHNWRDSLSFFASDLFKQVQMAQLFPDSKTFADAIVKTDLNTVLGAYDKACLEAQE
SGEAVDLASFVNSHFDIPEMISATSQTEFANVADYIEHMWQVLTRTPDTEQKDSLIALTR
PYIVPGGRFREIYYWDTYFTALGLIDAGRTDMAINMLVNFVDILNEVGCIPNGNRAYYYS
RSQPPILALFYNLLKDALSDQQKEYVIWGLKKEYQFWMNGAGENASQKSAAQLRTVTMPC
GAILNRYFDTEPTPRPESYREDIETAEHIGADKSQFYQHVRAACESGWDFSSRWLANPDS
LASIRTTEIIPVDLNALLVTLEQTLASVTKGAEQARFNTAATARINAINTYLFNAEKAGY
FDYHFPTQTQTNVVSAAMCVPLFVGIANDQQAEGVRAIVMNTLLKEGGVVTTSNTTSQQW
DAPNGWAPLQLFAVEGLRNYGFDMQAQTIMLRFCKTIENHFATSGVVLEKYNVCDPEIKA
GGGEYDVQLGFGWTNGVYTRFQSYLNQ