Protein Info for MIT1002_00156 in Alteromonas macleodii MIT1002

Annotation: Flavin mononucleotide phosphatase YigB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 246 PF00702: Hydrolase" amino acids 11 to 209 (199 residues), 49.5 bits, see alignment E=1.1e-16 PF13419: HAD_2" amino acids 121 to 214 (94 residues), 26.2 bits, see alignment E=1.1e-09 TIGR01549: HAD hydrolase, family IA, variant 1" amino acids 135 to 209 (75 residues), 37.8 bits, see alignment E=1.2e-13 PF13242: Hydrolase_like" amino acids 171 to 241 (71 residues), 31.7 bits, see alignment E=1.7e-11

Best Hits

KEGG orthology group: K07025, putative hydrolase of the HAD superfamily (inferred from 71% identity to amc:MADE_00202)

Predicted SEED Role

"Putative FMN hydrolase (EC 3.1.3.-); 5-Amino-6-(5'-phosphoribitylamino)uracil phosphatase" (EC 3.1.3.-)

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.1.3.-

Use Curated BLAST to search for 3.1.3.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (246 amino acids)

>MIT1002_00156 Flavin mononucleotide phosphatase YigB (Alteromonas macleodii MIT1002)
MQFFRSINSVEAMTFDLDDTLYNNEPIIRCAEQALQAHIAEHHQQAAKLTSLDWLQLKRA
AIAKDARLASDMGQLRRVVLSAALSGTPANQLSIVPTEDTALRAAVDSCFNCFYDARSDF
ALASNVHHTLDKLSQHLPLVGITNGNVNAQKVGLDRYFTAILHASVERPMKPAQNMFDEA
ASLIKVTPPHILHVGDNIIKDVFGAINAGYQSAWFACNRPMQLKLEPVSVLPHVQLDSLE
ELIQFV