Protein Info for MCAODC_07025 in Escherichia coli ECRC101

Name: sgcC
Annotation: PTS galactitol transporter subunit IIC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 452 transmembrane" amino acids 12 to 35 (24 residues), see Phobius details amino acids 46 to 64 (19 residues), see Phobius details amino acids 97 to 120 (24 residues), see Phobius details amino acids 140 to 163 (24 residues), see Phobius details amino acids 183 to 204 (22 residues), see Phobius details amino acids 224 to 247 (24 residues), see Phobius details amino acids 253 to 273 (21 residues), see Phobius details amino acids 300 to 330 (31 residues), see Phobius details amino acids 336 to 355 (20 residues), see Phobius details amino acids 363 to 385 (23 residues), see Phobius details amino acids 421 to 443 (23 residues), see Phobius details PF03611: EIIC-GAT" amino acids 14 to 398 (385 residues), 319.2 bits, see alignment E=2.1e-99

Best Hits

Swiss-Prot: 41% identical to PTKC_ECO57: PTS system galactitol-specific EIIC component (gatC) from Escherichia coli O157:H7

KEGG orthology group: K02775, PTS system, galactitol-specific IIC component (inferred from 100% identity to ecc:c4279)

MetaCyc: 49% identical to D-arabinitol/D-xylitol PTS component EIIC (Listeria monocytogenes)
2.7.1.-; 2.7.1.-

Predicted SEED Role

"Putative carbohydrate PTS system, IIC component (EC 2.7.1.69)" (EC 2.7.1.69)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.1.69

Use Curated BLAST to search for 2.7.1.69

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (452 amino acids)

>MCAODC_07025 PTS galactitol transporter subunit IIC (Escherichia coli ECRC101)
MNDIAHTLYNIVQYILGFGPTVMLPLVLFILALCFKVKPAKALRSSLTVGIGFVGIYAIF
DILTSNVGPAAQAMVERTGINLPVVDLGWPPLSAITWGSPIAPFVIPLTILINVAMLALN
KTRTVDVDMWNYWHFALAGTLVYYSTGSLFFGLLAAAIAAVVVLKLADWSAPLVQKYFGL
EGISLPTLSSVVFFPVGLLVDKIIDHIPGLNRIHIDPETVQKKFGIFGEPMMVGTILGIL
LGVIAGYDFKKVLLLGISIGGVMFILPRMVRILMEGLLPLSEAIKKYLNAKYPDRDDLYI
GLDIAVAVGNPAIISTALLLTPISVFIAFVLPGNEVLPLGDLANLAVMASMIALASRGNI
FRTVLAAIPVIIADLWIATKIAPFITGMAKDVNFKFAEGSSGQVSSFLDGGNPFRFWLLE
IFNGNLIAIGLVPVIALVLYGIFRMTRSTVYA