Protein Info for LU632_RS14980 in Erwinia tracheiphila SCR3

Annotation: IS4 family transposase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 440 PF13006: Nterm_IS4" amino acids 18 to 107 (90 residues), 98.5 bits, see alignment E=2.1e-32 PF01609: DDE_Tnp_1" amino acids 124 to 350 (227 residues), 93 bits, see alignment E=2.1e-30

Best Hits

Swiss-Prot: 55% identical to INSG_ECOLI: Transposase InsG for insertion sequence element IS4 (insG) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 86% identity to ddd:Dda3937_03988)

Predicted SEED Role

"Mobile element protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (440 amino acids)

>LU632_RS14980 IS4 family transposase (Erwinia tracheiphila SCR3)
MELSQALGIINAATPERARSLADLIPPELIQQALTLTDTVTLRKRKLSLESMIWLVVGMS
IFCDHPMTEIVNLMDITDRTGAPFTARSAVIQRRKTLGENAVRELFDITQQHWNQQAAHP
KWHGLNLFAVDGVVWRTADTPENRAVFSKHSSQYGEGGYPQVRMVCLMELSSHLIAASAF
DSEKVSEMRLAEHLTEKTPNNSITLFDKGFYSMGLLHHWQTAGEHRHWLLPLKKHVQYQV
VRRLGRGDELICLKTSPRARKQWPGIPEEMVARLLTRRVDGKERQVLTSLTDPNRYPGKD
ISELYRHRWEIELGYREAKQGMLDSRWTLRSRLPELVRQELWGVLLAYNLVRYQMVQMAF
HLKGDYLPYQLSFSGAISEIIRMLITLPWASPGKMPGELRTLYEQAKWLVLPGRRERSYP
RELRVKSRKYPDKKVAGHLK