Protein Info for LU632_RS09495 in Erwinia tracheiphila SCR3

Annotation: efflux transporter outer membrane subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 518 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR01845: efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family" amino acids 17 to 492 (476 residues), 402.4 bits, see alignment E=1.3e-124 PF02321: OEP" amino acids 74 to 281 (208 residues), 100.4 bits, see alignment E=5.4e-33 amino acids 307 to 491 (185 residues), 141.2 bits, see alignment E=1.7e-45

Best Hits

KEGG orthology group: None (inferred from 78% identity to ebi:EbC_14400)

Predicted SEED Role

"Outer membrane component of tripartite multidrug resistance system" in subsystem Multidrug Resistance, Tripartite Systems Found in Gram Negative Bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (518 amino acids)

>LU632_RS09495 efflux transporter outer membrane subunit (Erwinia tracheiphila SCR3)
MNVFPYIARSRISVLLVATLAMSACSVGPDYHAPTPATPGAFNSMASDRASRPQAAAINP
AWWKSFNDPQLDSLIERAIAGNLSLQQAVLRIACSRQQLNQARGAWLPSINGKISAQRQQ
MGLKGILESKGVYQQVNHTNPQLSSSLDDLTKSVGLYQGSFDASWELDLWGKVRRQVEAA
DAQQQVSLESRNDALVSLEAEVARTWLQLRGAQAIAQTLQNQIEMAQQTLTLTESQQKNG
LAPALDVEKARAQLSSLRAQQPQYEAQIHQAMNGLAVLIGQPPGALDNELAAARPMPALP
NIVPVGLPSTLARRRPDVRQAEARLHEATANIGVSVAQLFPDISLSGQFGMRNTDISYLD
NWSSHFYSVGPSVSVPIFQGGRLVAGVKMARAEQASAALDYRQTVLTALQDVENALISYR
TDQQQVEGLDQIVNAFQNAFNLANDSYAKGLSSFIDALDAQRQLSQAQQQAISARVQSSL
DLVALYKALGGGWELYQNVNLPDYSVFGPAESGDTPAG