Protein Info for LU632_RS05500 in Erwinia tracheiphila SCR3

Annotation: sugar porter family MFS transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 451 signal peptide" amino acids 1 to 26 (26 residues), see Phobius details transmembrane" amino acids 43 to 63 (21 residues), see Phobius details amino acids 71 to 89 (19 residues), see Phobius details amino acids 96 to 117 (22 residues), see Phobius details amino acids 129 to 147 (19 residues), see Phobius details amino acids 159 to 178 (20 residues), see Phobius details amino acids 238 to 261 (24 residues), see Phobius details amino acids 277 to 298 (22 residues), see Phobius details amino acids 307 to 329 (23 residues), see Phobius details amino acids 336 to 360 (25 residues), see Phobius details amino acids 372 to 394 (23 residues), see Phobius details amino acids 405 to 423 (19 residues), see Phobius details TIGR00879: MFS transporter, sugar porter (SP) family" amino acids 1 to 434 (434 residues), 478.9 bits, see alignment E=9.1e-148 PF00083: Sugar_tr" amino acids 5 to 437 (433 residues), 464.5 bits, see alignment E=8.3e-143 PF07690: MFS_1" amino acids 10 to 294 (285 residues), 123.1 bits, see alignment E=2.6e-39 amino acids 274 to 430 (157 residues), 37.8 bits, see alignment E=2.2e-13 PF06609: TRI12" amino acids 22 to 188 (167 residues), 41.1 bits, see alignment E=1.7e-14

Best Hits

Swiss-Prot: 83% identical to GALP_ECOL6: Galactose-proton symporter (galP) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: K08137, MFS transporter, SP family, galactose:H+ symporter (inferred from 92% identity to eta:ETA_28270)

MetaCyc: 83% identical to galactose:H+ symporter (Escherichia coli K-12 substr. MG1655)
RXN0-7077; TRANS-RXN-21

Predicted SEED Role

"Arabinose-proton symporter" in subsystem L-Arabinose utilization

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (451 amino acids)

>LU632_RS05500 sugar porter family MFS transporter (Erwinia tracheiphila SCR3)
MTFFVCFLAALAGLLFGLDIGVIAGALPFIAKDFNVSAHQQEWIVSSMMSGAAIGAIGSG
WLSSRLGRKKSLMIGAVLFVIGSLWSALATNPDMLIMARVLLGLAVGVASYTAPLYLSEI
APEKIRGSMISLYQLMITIGILGAYLSDTAFSFSGEWRWMLGVITIPAALLLVGVFFLPN
SPRWLAAKGDFRSAQRVLDRLRDTSEQAKRELDEIRESLKIKQFGWSLFKNNSNFRRAVY
LGILLQVMQQFTGMNVIMYYAPKIFEIAGFTNTTEQMWGTVIVGFINVLATFIAIGLVDR
WGRKPTLIMGFLVMALGMGILGTMLHVGIHSTGTQYFAIAMLLMFIVGFAMSAGPLIWVL
CSEIQPLKGRDFGITVSTATNWIANMIVGATFLTMLNSLGNANTFWVYAALNLFFIVLTV
SLIPETKNVSLEHIERNLLSGKKLRDIGQRD