Protein Info for LU632_RS04940 in Erwinia tracheiphila SCR3

Annotation: TIGR03747 family integrating conjugative element membrane protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 252 transmembrane" amino acids 28 to 49 (22 residues), see Phobius details amino acids 144 to 178 (35 residues), see Phobius details amino acids 205 to 223 (19 residues), see Phobius details amino acids 229 to 248 (20 residues), see Phobius details TIGR03747: integrating conjugative element membrane protein, PFL_4697 family" amino acids 18 to 252 (235 residues), 317.9 bits, see alignment E=2e-99 PF14348: DUF4400" amino acids 54 to 249 (196 residues), 244.3 bits, see alignment E=4e-77

Best Hits

KEGG orthology group: None (inferred from 92% identity to eic:NT01EI_0337)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (252 amino acids)

>LU632_RS04940 TIGR03747 family integrating conjugative element membrane protein (Erwinia tracheiphila SCR3)
MAEPQRNSPPPPRPEKPHGLLYNVFWDWPWALIGMLLGSLMLSLLIEYTGIAFFWPEAGA
AHSEAVMNTELGWLSTEFTRSLLLSEPSVTVVKWVTVAYQWLFVDSGFTGWIKQQNVLQT
GSDNELTRNLNNWSGWLAGYLHEYLMATVWICVITLVRVTILVLSVPLFLMVVLVSLVEG
LGRRDLRRYGAGYESSFVYHHAKKMVKPVIVVPMMLYLSWPTAVYPNLLLLPAAILLGVA
ITVTTASFKKYL