Protein Info for LU632_RS02715 in Erwinia tracheiphila SCR3

Name: lptD
Annotation: LPS assembly protein LptD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 signal peptide" amino acids 1 to 37 (37 residues), see Phobius details PF03968: LptD_N" amino acids 66 to 207 (142 residues), 82.7 bits, see alignment E=2.4e-27 PF04453: LptD" amino acids 326 to 713 (388 residues), 382.5 bits, see alignment E=2.9e-118

Best Hits

Swiss-Prot: 68% identical to LPTD_PECAS: LPS-assembly protein LptD (lptD) from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672)

KEGG orthology group: K04744, LPS-assembly protein (inferred from 87% identity to ebi:EbC_06940)

Predicted SEED Role

"Outer membrane protein Imp, required for envelope biogenesis / Organic solvent tolerance protein precursor"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (800 amino acids)

>LU632_RS02715 LPS assembly protein LptD (Erwinia tracheiphila SCR3)
MMPVITEFSIPRMKKRLPTLLASLIGTALYSQQGLADVLASQCMLGVPGYTRPLIQGKNN
NDLPVTINADQAKGRYPDNAVFTGNVDVQQGNGRLQSDEIQLHQKQVQGQTTLVRTVDAL
GNVHYDDDQVVLRGPKGWSNLNTKDTNVWNGDYQMVGRQGRGTADQMKLRGQNRYTILEN
GTFTSCLPGDNSWSVAGTHIIEDREEQVAEIWNARFRIGKVPVLYSPYLQLPIGDRRRSG
FLIPNAKYDSSNGFEFILPYYWNIAPQVDATITPHYMSNRGTQLQNEFRYLTKAGEGLME
FDYLPSDRQYTKDATSRNITNSDDSDRWMFTWKHNGVYDQNWRFNIDYTKVSDVYYFTDL
ESPYASSTDGYVTQKFSVGYAEQNWDATLSTKQFQIFSTQTNNDVYRAEPQFDFNYYQND
VGPFDTHLYAQAVKFTNVNEAYPDAIRLHLEPTINLPLSNHWGSLNTEAKLLATHYQQND
IEYWNESVDSSKVNQLKSSVNRVMPQFKVDGKMVFDRDMDWSPGYTQTLEPRVQYLYVPY
RDQSDIRAYDSTLLQSDYTGLFRDRTYSGLDRIPSANQITTGVTTRIFDNDLVERFNASV
GQIYSFTPSRTGLETTDSDDRGSIEWAGDSFWKISERWNARGGVQYDTRLRTVSQGSAVL
EYRRDADRLVQLNYRYTSPEYIQQTLSQITNPGYQQGISQVGATASWPIADSWAVVGAWY
YDIKAKQPADQFLGLQYNSCCYAIRMGYERKITSWDSANSKSNYDNKISFNIELRGLSPS
YSLGTGEMLRQGILPYQRSF