Protein Info for LU632_RS00455 in Erwinia tracheiphila SCR3

Name: sctW
Annotation: type III secretion system gatekeeper subunit SctW

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 373 TIGR02568: type III secretion regulator YopN/LcrE/InvE/MxiC" amino acids 43 to 262 (220 residues), 107.6 bits, see alignment E=4.1e-35 PF07201: HrpJ" amino acids 48 to 208 (161 residues), 90.1 bits, see alignment E=1e-29

Best Hits

KEGG orthology group: K04058, type III secretion protein SctW (inferred from 56% identity to eay:EAM_2666)

Predicted SEED Role

"Type III secretion outermembrane contact sensing protein( yopN,Yop4b,LcrE)" in subsystem Type III secretion systems, extended

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (373 amino acids)

>LU632_RS00455 type III secretion system gatekeeper subunit SctW (Erwinia tracheiphila SCR3)
MSIRIPGSVDIKNIDDRSAANTAKNNKVVAENTVYEPVVDLQSELFNASEELSGMLSMFG
RFNRTNRKNISEENDYYSSILEDHAEEKLDTLIKQVPRLQTQNNILNFARGLFPDDSDLM
MALRQLLLSRWVSELAKKKIKEAIKDLEKFGEQQKMRSGINVASLAKRFSTQGDTRPLTA
KDLRNSYLRFLGLNIPAGFIYQDWIDEFGFENRKRLLVFTLSALIADMKANEPGIHFAEF
GPLNAKLSDARVLHTLDLLLNDNFRALTFYDQLKNENQPISEDDVVGLYMKGIVNCTGFK
PQLKKFNDQFMSSLFIKQRAEVIQSLHKIYKMTPAFIFPQEIFKDEILNMILLLSDDIYK
REKKTGIWSEYYK