Protein Info for LRK53_RS17205 in Rhodanobacter sp000427505 FW510-R12

Annotation: fumarylacetoacetate hydrolase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 328 PF18288: FAA_hydro_N_2" amino acids 1 to 78 (78 residues), 96.6 bits, see alignment E=9.7e-32 PF01557: FAA_hydrolase" amino acids 83 to 323 (241 residues), 112.4 bits, see alignment E=2.6e-36

Best Hits

KEGG orthology group: None (inferred from 79% identity to psu:Psesu_2469)

Predicted SEED Role

"Fumarylacetoacetate hydrolase family protein" in subsystem Gentisare degradation or Salicylate and gentisate catabolism

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (328 amino acids)

>LRK53_RS17205 fumarylacetoacetate hydrolase family protein (Rhodanobacter sp000427505 FW510-R12)
MKLGTLKDGGRDGTLVVVSRDLSCAVKAAGIAPTLQAALDDWSNAAPRLNALSEELNAGG
AAGAFALDMAALASPLPRAYEFVDGSAYLPHVERVRRARGAEVPASFYTDPLMYQATSAG
FLSPRDPVVVPSEGYGIDLEAEVVVVTDDVPMAVTPGEASAHIQLVGLVNDVSLRGLIPG
ELAKGFGFLQSKPRSALSPVLATPDELGDAWAGDKLHLPMRTWLNGAWFGEAECGVDMQF
SFAELVAHVAKTRPLTAGTIVGSGTIANQDTGKGASCLAEQRTVETLRDGHPSTPFLKFG
DRLKIDVTDAAGASIFGAIEQRIEAYRR