Protein Info for LRK53_RS16660 in Rhodanobacter sp000427505 FW510-R12

Annotation: tetratricopeptide repeat protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 628 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 61 to 82 (22 residues), see Phobius details amino acids 94 to 107 (14 residues), see Phobius details amino acids 310 to 339 (30 residues), see Phobius details PF13519: VWA_2" amino acids 100 to 203 (104 residues), 31.4 bits, see alignment E=5.2e-11 PF07719: TPR_2" amino acids 405 to 437 (33 residues), 35.2 bits, see alignment (E = 1.5e-12) PF00515: TPR_1" amino acids 405 to 437 (33 residues), 39.1 bits, see alignment (E = 8.4e-14) PF13414: TPR_11" amino acids 411 to 440 (30 residues), 32.2 bits, see alignment (E = 1.3e-11)

Best Hits

Predicted SEED Role

"TPR domain protein in aerotolerance operon"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (628 amino acids)

>LRK53_RS16660 tetratricopeptide repeat protein (Rhodanobacter sp000427505 FW510-R12)
MNELLQQFHFLRPWWLAALLLLPLLGWFGVRRNVAQVELSRLVDAELLPHLLYGRAGNRS
LPLWLFALGWILCALALAGPTWSRVEQPLYASRAAQVVAISLSQHMLARDVAPSRLDRAR
YKARDLLHANQDGLNALVGYAGEAFVVAPLTSDAHSLDDLLAAMAPDTMPVDGDNAAAAI
ERGVALIQDAKAGGGSLVLITDQVEVTATAAARKADAAGVRVSVLGVGTPQGGPVPLSDG
GFLRDAQGGMLLARRDDAALAALAAAGGGHYVAMGADQRDVDALHAQLQSTRATLADGQH
GDQWQDRGAWLLLPLLPLAALAFRRGWLLVLPLAVLPLWPGTAAATSWHDLWRRPDQQAA
QALRAGDAKRAQQLARDPAWRGAAAYRAGDYAAAAQALPQAPGSDAAYNLGNTLAKQGEY
QQALAAYDRALKLDPANADAKANRQAVEDWLRRQQQQPSDQKEHEGHGGKQNQSSQGEQG
KSGKQDAKDSASAPDNAGPSGQPGQNGKSQEQDPSGKDASQQGKSGQGGAALPKPQSAQQ
QAEQKAQAEQAQQALKQQMDAELAKPDDDKAGHQLGTLAKDDPQAKLPADLRHALQRVPD
DPGALLRRKFELEYQQRHGGAPSEDQQP