Protein Info for LRK53_RS16065 in Rhodanobacter sp000427505 FW510-R12

Annotation: DUF4105 domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 334 signal peptide" amino acids 1 to 32 (32 residues), see Phobius details transmembrane" amino acids 44 to 63 (20 residues), see Phobius details amino acids 70 to 87 (18 residues), see Phobius details PF13387: DUF4105" amino acids 128 to 280 (153 residues), 145.5 bits, see alignment E=6.5e-47

Best Hits

KEGG orthology group: None (inferred from 56% identity to vpe:Varpa_2987)

Predicted SEED Role

"putative membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (334 amino acids)

>LRK53_RS16065 DUF4105 domain-containing protein (Rhodanobacter sp000427505 FW510-R12)
MAKKRGMIGRVALFAAVSLASFVSGAWGAMALWYQLPGNATVRTLGGTLWALAVIALAAV
AMVRRSWLPLGVYTAMYALLLLWWAGIAPSGTRVWADDVARQFTGTVSGSEVTLDNVRDF
DWRSDDDYDARWETRHYDLDHLASADAVLSYWGSRAIAHAMLSFGFDDGNRVVFSVEIRR
QRGEQYSPIGGFFKQFETVLVAADEHDIIRVRTNVRGEDDYLYPLRMDKAAMRRLFLSYV
QAANTLAGRPAFYNTITSNCTTIVYRMARQIEPGLPWDIRLLLTGYLPGYLHEVGAVDRS
VPLDELRRRSRITERARNTAAGDDFSRAIRAHES