Protein Info for LRK53_RS14940 in Rhodanobacter sp000427505 FW510-R12

Annotation: response regulator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 120 PF00072: Response_reg" amino acids 4 to 115 (112 residues), 93.5 bits, see alignment E=4.9e-31

Best Hits

Swiss-Prot: 38% identical to CHEY_CAMJE: Chemotaxis protein CheY homolog (cheY) from Campylobacter jejuni subsp. jejuni serotype O:2 (strain ATCC 700819 / NCTC 11168)

KEGG orthology group: K03413, two-component system, chemotaxis family, response regulator CheY (inferred from 69% identity to hch:HCH_00454)

Predicted SEED Role

"Chemotaxis regulator - transmits chemoreceptor signals to flagelllar motor components CheY" in subsystem Bacterial Chemotaxis or Flagellar motility or Two-component regulatory systems in Campylobacter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (120 amino acids)

>LRK53_RS14940 response regulator (Rhodanobacter sp000427505 FW510-R12)
MAKILAVDDSVSMRGMVAFTLRGAGHEVAEAENGQLALDVARGSSFDLVLADVNMPVMDG
IAMVRELRAMDAYKGVPILMLTTESHTEKKMEGKAAGATGWLVKPFDPEQLLATVKRVLG