Protein Info for LRK53_RS14770 in Rhodanobacter sp000427505 FW510-R12

Annotation: SDR family NAD(P)-dependent oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 256 PF00106: adh_short" amino acids 23 to 214 (192 residues), 109 bits, see alignment E=3.4e-35 PF08659: KR" amino acids 25 to 158 (134 residues), 43.6 bits, see alignment E=4.9e-15 PF13561: adh_short_C2" amino acids 29 to 214 (186 residues), 81.9 bits, see alignment E=8.3e-27

Best Hits

KEGG orthology group: None (inferred from 50% identity to smt:Smal_1375)

MetaCyc: 41% identical to CAI-1 synthase (Vibrio cholerae O1 biovar El Tor str. N16961)
1.1.1.-

Predicted SEED Role

No annotation

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (256 amino acids)

>LRK53_RS14770 SDR family NAD(P)-dependent oxidoreductase (Rhodanobacter sp000427505 FW510-R12)
MTTLRTSHLPTGWQPAADTLADRVVLVTGAYGGLGGAVARAASRAGATVVITGKRKRQLE
QLYDAMLAEGLAEPVIHPLDMEVATPRDYATLAEGLERDFGRLDGIVHAAVSFGGLTPIS
MHKPDAWLRSMHVNVNAPFALTQACLPLLTQAADSAVVFVLDDPALLQRAHWGGYGASKA
ALERFVAILHEETDSGPLRTHAMLPAPMRTALRQLAYFGEDILQRPLPDAAAAAAVYLLG
VQGAAARGTVLDLRAG