Protein Info for LRK53_RS14645 in Rhodanobacter sp000427505 FW510-R12

Annotation: molybdopterin molybdotransferase MoeA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 417 PF03453: MoeA_N" amino acids 4 to 168 (165 residues), 132.9 bits, see alignment E=1.3e-42 TIGR00177: molybdenum cofactor synthesis domain" amino acids 178 to 318 (141 residues), 96.4 bits, see alignment E=7.9e-32 PF00994: MoCF_biosynth" amino acids 181 to 321 (141 residues), 115.9 bits, see alignment E=1.9e-37

Best Hits

KEGG orthology group: K03750, molybdopterin biosynthesis protein MoeA (inferred from 56% identity to xom:XOO_2952)

Predicted SEED Role

"Molybdopterin biosynthesis protein MoeA" in subsystem Molybdenum cofactor biosynthesis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (417 amino acids)

>LRK53_RS14645 molybdopterin molybdotransferase MoeA (Rhodanobacter sp000427505 FW510-R12)
MIGYHDALALILERTRRLPERRCPLEQALGRLLARSVSSPAELPPFDNAAMDGFALHAGD
ARLPAGSEHVVMGAQAAGDALAQAAGGAWEIMTGARMPAGMDTVVPVEQVEIVEHDGDGR
PRRIRLGIDVEAGRHVRRCGEDVPLGAELMPAGELLQAQHLALLAALGVAEVPVVRRPRV
AIICTGRELVDDPGQPLQSGQIRNSNGPFLAARLAAAGAQVVYRQTVQDDPAAFVRALGE
ALHAGATVVLSTGAVSMGRHDFVPEALRELGAQIHFHKLRIRPGKPLLFASLPDGALFFG
LPGNPVSSAVGLRFFVEPALRGMLGLPPERPLRLPLQQRFEQRVPLRCFLKGKLALAADG
RLQAVLLDGQESFRIRPLLDTGAWVVLAEDAQVREPGSMVEVYALGHLQPLAIGGEA