Protein Info for LRK53_RS14550 in Rhodanobacter sp000427505 FW510-R12

Annotation: PLP-dependent cysteine synthase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00291: PALP
  • amino acids 35 to 326 (292 residues), 168.7 bits, E=9.9e-54

Best Hits

KEGG orthology group: K01738, cysteine synthase A [EC: 2.5.1.47] (inferred from 58% identity to sna:Snas_0817)

Predicted SEED Role

"Cysteine synthase B (EC 2.5.1.47)" in subsystem Cysteine Biosynthesis (EC 2.5.1.47)

MetaCyc Pathways

• superpathway of sulfate assimilation and cysteine biosynthesis (9/9 steps found)
• L-cysteine biosynthesis I (2/2 steps found)
• seleno-amino acid biosynthesis (plants) (2/5 steps found)
• superpathway of seleno-compound metabolism (5/19 steps found)

KEGG Metabolic Maps

• Cysteine metabolism
• Selenoamino acid metabolism
• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 2.5.1.47

Use Curated BLAST to search for 2.5.1.47

Protein Sequence (368 amino acids)

>LRK53_RS14550 PLP-dependent cysteine synthase family protein (Rhodanobacter sp000427505 FW510-R12)
MDSVLRLVNPQRETDLRWVHTALAKLAQEAARSADTHLLKLNFPGFHGIDFYFKDEAAHP
SGSLKHRLARSLFLYVLCNGWLRGGQTVVDASSGSTAIAEAWFARLLGLPFIAVMPACTA
PGKIRDVQALGGECDLVDDPAQVHARAAKHAAQGACHLDQFGLAERATDWRGNNNIAESI
IGQLVLEAEPEPAWIVCGAGTGGTSATIGRYLRYRRLHTQLCVAEPSGSGYVHGWRSRDT
QAVASQPTLIEGIGRPRVEPGFIFDVVDRVIEIPDAASIAAAWLLEELIGHRYGGSSGTN
LVACLQLAASMRARGERGSIVSLLCDRGERYAQTLFDPDWLAAHDIDLAPWTAALRTSLA
SGRSPITA