Protein Info for LRK53_RS13345 in Rhodanobacter sp000427505 FW510-R12

Annotation: M48 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 265 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details PF01435: Peptidase_M48" amino acids 80 to 242 (163 residues), 129.4 bits, see alignment E=7.2e-42

Best Hits

KEGG orthology group: None (inferred from 49% identity to kko:Kkor_0340)

Predicted SEED Role

"Zn-dependent protease with chaperone function PA4632"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (265 amino acids)

>LRK53_RS13345 M48 family metallopeptidase (Rhodanobacter sp000427505 FW510-R12)
MKFRNLTIPLATALLAACVTSPTGRSQLMMVSDSQMSQMGLSAFNDMRKQGKFVDAPREH
AYATCVSNALIAVLPPPWNTQQWEVQIIGDDTANAFALPGGRIGVNRGMFKIATNQDQLA
VVLGHELSHVVSRHGAERVSDNMAAQAAVAAGTIYAGSRGSDAGNAAALLGVGAEVGILL
PFSRTQESEADTLGQRYMAQAGFDPRAAAALWGKMGAQGGGKPPAFLSTHPSSGNRAQAL
DRQAQQLLPVYQQARASGHAPNCRM