Protein Info for LRK53_RS11700 in Rhodanobacter sp000427505 FW510-R12

Annotation: replication-associated recombination protein A

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 445 PF05496: RuvB_N" amino acids 26 to 149 (124 residues), 49.8 bits, see alignment E=1e-16 PF00004: AAA" amino acids 59 to 168 (110 residues), 56.9 bits, see alignment E=9.2e-19 PF16193: AAA_assoc_2" amino acids 194 to 268 (75 residues), 87.6 bits, see alignment E=1.6e-28 PF12002: MgsA_C" amino acids 270 to 434 (165 residues), 218.7 bits, see alignment E=1.4e-68

Best Hits

Swiss-Prot: 57% identical to RARA_COXBU: Replication-associated recombination protein A (rarA) from Coxiella burnetii (strain RSA 493 / Nine Mile phase I)

KEGG orthology group: K07478, putative ATPase (inferred from 75% identity to psu:Psesu_1544)

Predicted SEED Role

"FIG065221: Holliday junction DNA helicase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (445 amino acids)

>LRK53_RS11700 replication-associated recombination protein A (Rhodanobacter sp000427505 FW510-R12)
MPRPVPTPGAGLFAEPDALKPLAERMRPRSLDEIVGQQRLVGPDKALRRALEAGKIHSMV
LWGPPGCGKTTLALLVARYADADFRAISAVLSGLPDVRKALAEAELNFTQGRRTVLFVDE
VHRFNKTQQDAFLPHIERGVIIFIGATTENPSFELNSALLSRCRVHVLEPVSTGDIIAAL
KRALVDDERGLGALQLQVSEEALDSIAQAADGDVRRALTLLEIAAELAEDRRIDEATLTQ
VLADRTRRFDKQGEQFYDQISALHKSVRSSDPDAAVYWLCRMLDGGVDPLYLARRMTRMA
VEDVGLAEPRAWRMALDAWDTYERLGSPEGELGLAQLAIWLAVAPKSNAAYMAYNKARDA
VRQGGTLEVPMHLRNAPTKLMKGLGYGKGYQYDHDAEGGIALDQQCLPDALAGSIFYEPV
ERGLELQLREKLLALRAARKKVRKA