Protein Info for LRK53_RS08720 in Rhodanobacter sp000427505 FW510-R12

Annotation: hydantoinase/oxoprolinase family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 698 PF05378: Hydant_A_N" amino acids 8 to 185 (178 residues), 155.1 bits, see alignment E=2.5e-49 PF01968: Hydantoinase_A" amino acids 207 to 499 (293 residues), 300.9 bits, see alignment E=1.4e-93 PF19278: Hydant_A_C" amino acids 513 to 683 (171 residues), 58.6 bits, see alignment E=8.3e-20

Best Hits

KEGG orthology group: K01473, N-methylhydantoinase A [EC: 3.5.2.14] (inferred from 68% identity to reu:Reut_B5474)

Predicted SEED Role

"N-methylhydantoinase A (EC 3.5.2.14)" in subsystem Hydantoin metabolism (EC 3.5.2.14)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 3.5.2.14

Use Curated BLAST to search for 3.5.2.14

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (698 amino acids)

>LRK53_RS08720 hydantoinase/oxoprolinase family protein (Rhodanobacter sp000427505 FW510-R12)
MSTPVTIRVATDVGGTFTDLVYFRTDPHNGHQEVITAKTDTTPPNFERGVLNVITKAKVP
VREVAFLAHGTTVVINALTERKGVKVALITTEGFRDTLEIARGNRPDFFNLGYRKPESFV
PRHLRRELPGRIGPNGAERTPLDLSALPAIVEDFRREGVVAIAVCLLHSYANPAHEVRVL
DEVRRLWPEVSTVASHQITREWREYERTNTAVLSAYVQPIAGRYLADLKRGLNDEGLAGQ
LYVMQSNCGVDSIERASRIPITMVESGPASGFWGAAELGRLIGEPNLLALDIGGTTAKCS
LIENGQVRIMTDYWIERGATSAGYPIMVPVVDLVEIGNGGGSIAWLDEFGKLRVGPKSAG
STPGPAAYGRGGTQATTTDANLALRRINPEYFCGGTIQADLGAVDRALAPLAAGLGMSPI
EVARGIVRIANHNMVNALKLVSMNRGHDPRDFTLVAFGGGGPMHAVSLATELNMRRVVIP
RAADVFSAWGMLMSELRRDFFVSRLIPLDGTNAGAIEALFGESTAMALEQFGTEGIAPER
VKFLRYAKLRYENQEHHVEVMMPDGALDADAIASITIGFHQVYEREYTYRLNAAVEFIGL
HLVALADVGKLQPAKLPVSGRKVSEALKSRRDVDYATQGEHTADIYDGALLEPGMQFRGP
AVIETSGTTILIHPGNRVRIDDYGNVIVDLDTEEFRHD