Protein Info for LRK53_RS08150 in Rhodanobacter sp000427505 FW510-R12

Annotation: efflux RND transporter periplasmic adaptor subunit

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 421 signal peptide" amino acids 1 to 30 (30 residues), see Phobius details PF25971: CzcB_N" amino acids 55 to 146 (92 residues), 78.9 bits, see alignment E=6.2e-26 PF25973: BSH_CzcB" amino acids 194 to 265 (72 residues), 40.1 bits, see alignment E=6.9e-14 PF25954: Beta-barrel_RND_2" amino acids 268 to 336 (69 residues), 34.4 bits, see alignment E=5.1e-12 PF25975: CzcB_C" amino acids 349 to 408 (60 residues), 55.2 bits, see alignment E=1.3e-18

Best Hits

KEGG orthology group: None (inferred from 63% identity to pau:PA14_31030)

Predicted SEED Role

"Probable Co/Zn/Cd efflux system membrane fusion protein" in subsystem Cobalt-zinc-cadmium resistance

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (421 amino acids)

>LRK53_RS08150 efflux RND transporter periplasmic adaptor subunit (Rhodanobacter sp000427505 FW510-R12)
MKFMSLKSAPIKRIALVLLVLATVALGACGDRAAHEPAAGEHAAADAFERGPHNGRLLRD
GSFALEVTVYEAGVPPEFRLYGYRDGKLLPPDALQPLIEIRRLDGETTRFTFRPEGDALV
ADGTVIEPHSFDVKVSAVHAGKTHAWNYASYEGRVTIPAAIAVASGVKTSVAGPATIRDV
LPLMGRVAIDRSRQAMVRARFPGIVRSVPVNLGDRVRRGQTLATVEGNDSMRSYTVTAPL
DGVVLARNTNVGDVAGEAPLFEIADLSSVWVELHAVGRDADRLRPGQAVRVRPASGGEAL
ATRIDALVPVTHMGTSVVARARILNPDGAWRPGMAVVGDVTVAQREVPLAVKVSGLQRFR
DFTVVFARVGDTYEVRMLELGARDAGAVEVLGGLKPGTAYVSEQSFLIRADIEKSGASHD
H