Protein Info for LRK53_RS07845 in Rhodanobacter sp000427505 FW510-R12

Annotation: UvrD-helicase domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1000 1100 1190 transmembrane" amino acids 1112 to 1128 (17 residues), see Phobius details amino acids 1150 to 1166 (17 residues), see Phobius details PF00580: UvrD-helicase" amino acids 18 to 430 (413 residues), 149.1 bits, see alignment E=5.2e-47 PF13245: AAA_19" amino acids 365 to 418 (54 residues), 25.1 bits, see alignment 4.4e-09 PF13361: UvrD_C" amino acids 721 to 818 (98 residues), 45.8 bits, see alignment E=1.5e-15 PF12705: PDDEXK_1" amino acids 953 to 1156 (204 residues), 30.8 bits, see alignment E=7.6e-11

Best Hits

Predicted SEED Role

"Exodeoxyribonuclease V beta chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1190 amino acids)

>LRK53_RS07845 UvrD-helicase domain-containing protein (Rhodanobacter sp000427505 FW510-R12)
MTATDATALPPLDWRAMPLHGRVLIEASAGTGKTWNIGVLYLRLLLERGLRVEQILVTTF
TDAAAQELRERLRRRLVEAERLLEAAARDVTSADPLESWLAALCPDADSVRLALRRIQLA
RSDLDRAPVSTIHALCQRIQRDYPLESGAAFADDQLFDEQQLMRECVEDFWRRRYLAGAV
DPREAELLLKDGPEGLLRDLGGLANSVDARIEAGGLTELDHALATLRGDDSIAELQRLAG
DATLYKRANAALRSRLGEITQALRNGDEAQLAKSISDVFEPDKLLAQAAAGRAGELAAHP
LIHALQTLRPLLGIRDILVRGEVLAAAAQTCRDEMPRRARQRQVLTFSMLIDAVYQRLCG
DASDDLLADRLFEAFPVALIDEFQDTDQRQFAIFERIYRERGTLVMIGDPKQAIYSFRGG
DIAAYLRAGEQAGQRFSLGTNHRSSRALVEALNAWYGHTEGGFGQPQIRYQPVEPAGKAD
EQPYTVDGQPVTLPLVIHPFRGDAVDVKSLGTLEALALDDCANRIAELLNDPRQAIGGRR
LTPGDVAVLLSTNKQIVALRQRLVARGVPCVGSGRGNIFAGEVARELELVLYAVLHADDD
QAVRGALATTLLGATLEQFHAWQAQAAAFERELERFEAWRALVRSRGVLALVGELLAARA
TALLMLPEGERVLTDLRHLGELLAAEEGARQGLDGLYAWLQEMRREGGDGDAEAADERQL
RIESDARRVQLLTIHASKGLEFPIVFLPLAWRIGDRNGPRAPKLLRYHDADGQRCVDLGS
AHFAGHRVRHFREELEERLRLLYVALTRAVHAVHVYWADRGLRPGDDAQAWAWAAIDLLL
GQAQRKLELPEGEASLAAMATALGGMQLAAPFADIYTRYRPPVEAPAPRATQAPLPQLRP
FQWLHSFSGLTRHAATLIEDSGSADETGAEEPAIEVGDDTEDGRLLALYPLRGPRFGDAV
HQVFELAQPGPLWPDQRQLLHRQLGAQAVAAPHLAHEEALERVGRMIDRARQADLGDGLR
LLDLAPDQRIAEFEFQFPVWQVPLAPLRRLCAAHGHAEAIPASLDATTLNGMLTGFVDLI
FARDGRFHVLDYKTNWLGARLRDYQGDSLAAAMTVHHYPLQALLYTVALHRYLRQRMDGY
TAERHLGESWYLFVRALGLAPGLGVWRRRWPAALVEALDDAFAGAQEAAA