Protein Info for LRK53_RS07470 in Rhodanobacter sp000427505 FW510-R12

Annotation: TRZ/ATZ family hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 PF01979: Amidohydro_1" amino acids 66 to 414 (349 residues), 219.4 bits, see alignment E=8.2e-69 PF07969: Amidohydro_3" amino acids 186 to 413 (228 residues), 59.2 bits, see alignment E=5.6e-20

Best Hits

Swiss-Prot: 48% identical to MTAD_TERTT: 5-methylthioadenosine/S-adenosylhomocysteine deaminase (mtaD) from Teredinibacter turnerae (strain ATCC 39867 / T7901)

KEGG orthology group: None (inferred from 72% identity to xcv:XCV2575)

Predicted SEED Role

"S-adenosylhomocysteine deaminase (EC 3.5.4.28); Methylthioadenosine deaminase" (EC 3.5.4.28)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.5.4.28

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (443 amino acids)

>LRK53_RS07470 TRZ/ATZ family hydrolase (Rhodanobacter sp000427505 FW510-R12)
MSQMPPQPVDLMIEARWVVPIEPHGVVLDNHAVAVDGGRIVAVLPMAEAHAAYAPRERVS
LSEHALIPGLVNSHTHNPMTLLRGLADDLPLMVWLQQHIWPAEAKVLGPEFVRDGVELAV
AEMLRGGTTCANENYFFPDVIGATYRKLGFRAVVGLPVIEFPTAWAKSQDEYFERAGEVY
DSFRGDHLISTAFAPHAPYTVSDESFERIRVLSDQLDIPVHLHTHETAHEVEDEKARSGL
RPFQRLQKLGLVNDRLIAVHMTQLTDGEIAACAAAGVSVVHCPESNLKLASGFCPAEKLR
VAGVNLALGTDGCASNNDLDMFGEMRTAALLAKAVAGDAAAFDAAFALRAATLNGAKAVG
LEAKIGSIEVGKQADFAAVRLSDLETQPLFHVVSQLVYATGRHQVSDVWIAGKRKLATRE
LVGMDTVAILERTRAWRERIASA