Protein Info for LRK53_RS05210 in Rhodanobacter sp000427505 FW510-R12

Annotation: type IV pilin protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 137 transmembrane" amino acids 6 to 28 (23 residues), see Phobius details PF07963: N_methyl" amino acids 2 to 23 (22 residues), 29.8 bits, see alignment 3.2e-11 TIGR02532: prepilin-type N-terminal cleavage/methylation domain" amino acids 2 to 24 (23 residues), 33 bits, see alignment 1.7e-12 PF16732: ComP_DUS" amino acids 25 to 119 (95 residues), 64.6 bits, see alignment E=1.3e-21

Best Hits

Swiss-Prot: 36% identical to FMPO_PSEAE: Fimbrial protein (pilA) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1)

KEGG orthology group: K02655, type IV pilus assembly protein PilE (inferred from 57% identity to reu:Reut_A0399)

Predicted SEED Role

"Type IV pilus biogenesis protein PilE" in subsystem Type IV pilus

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (137 amino acids)

>LRK53_RS05210 type IV pilin protein (Rhodanobacter sp000427505 FW510-R12)
MRGFTLIELMITVAVIAILAAIAVPSYFQYTLRSNRSAAESLMQEMASAQERYMVDSRAF
AGSRTVLGYGTLPNTVEPNYTIAMVATAASASGGTPPGYTITATPKGSQVRDTACAALTL
NGDGSKLASGGATNCWK