Protein Info for LRK53_RS05150 in Rhodanobacter sp000427505 FW510-R12

Annotation: cell envelope integrity protein TolA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 314 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details PF13103: TonB_2" amino acids 228 to 311 (84 residues), 22.2 bits, see alignment E=6.4e-09

Best Hits

Predicted SEED Role

"TolA protein" in subsystem Ton and Tol transport systems

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (314 amino acids)

>LRK53_RS05150 cell envelope integrity protein TolA (Rhodanobacter sp000427505 FW510-R12)
MDESKATPKAVVLSAVLHIGIVGFLFLAVLPCSTYENVFDALHLPTWMNPITCSKPLELQ
GPIIEATLIGPTGSPPPKAVKVKPVPDSTPPPPTVPPPTPPKIEAPEVKTLPPPPKQPDL
KDQERVVEEAALKAEEAKQLQEEKQRQRQAELDAQAAKQKQQKQKQIDDLIAKMDAAAQQ
TRKLDNRAKQAKQQLEDLKNAQDNGAPDLPNAAQRQTGNNSLNSNLADEYAAAIQNAVTP
NWLRPDNIPSVPCQVHIVQSPGGDVMSATVDSSCPYDDAGRRSVENAVLRTKTLPYKGFE
SVFQRNLTFTFRPQ