Protein Info for LRK53_RS05010 in Rhodanobacter sp000427505 FW510-R12

Annotation: beta-phosphoglucomutase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1007 PF03636: Glyco_hydro_65N" amino acids 31 to 282 (252 residues), 161.1 bits, see alignment E=9.1e-51 PF03632: Glyco_hydro_65m" amino acids 342 to 706 (365 residues), 362.3 bits, see alignment E=7.4e-112 PF03633: Glyco_hydro_65C" amino acids 716 to 772 (57 residues), 63.2 bits, see alignment 3.9e-21 TIGR01990: beta-phosphoglucomutase" amino acids 796 to 982 (187 residues), 220.9 bits, see alignment E=2.7e-69 TIGR02009: beta-phosphoglucomutase family hydrolase" amino acids 797 to 981 (185 residues), 177.7 bits, see alignment E=5.4e-56 PF00702: Hydrolase" amino acids 797 to 975 (179 residues), 98.5 bits, see alignment E=1.7e-31 PF13419: HAD_2" amino acids 799 to 980 (182 residues), 66.8 bits, see alignment E=6.8e-22 TIGR01509: HAD hydrolase, family IA, variant 3" amino acids 856 to 981 (126 residues), 61.9 bits, see alignment E=1.6e-20

Best Hits

Predicted SEED Role

"Maltose phosphorylase (EC 2.4.1.8) / Trehalose phosphorylase (EC 2.4.1.64)" in subsystem Maltose and Maltodextrin Utilization or Trehalose Biosynthesis or Trehalose Uptake and Utilization (EC 2.4.1.64, EC 2.4.1.8)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.4.1.64, 2.4.1.8

Use Curated BLAST to search for 2.4.1.64 or 2.4.1.8

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1007 amino acids)

>LRK53_RS05010 beta-phosphoglucomutase (Rhodanobacter sp000427505 FW510-R12)
MVDSYAAVLLDAEVPSVGAEVVIDPWLLVRHGTDPAGFAQDESLFALANGTLGVRGNLEE
SDSASQATLLSAVWERSPIDYHERFPGFAAHTDTRIPVADAARIHLRLGDTPVRLDQGTW
LHFERVLDLRQGCYRRRLRWRSPEGATLEIEAERIVSLEDAGLLAIHYRVRSLDYAGPIT
LESSISTAREAAEQGFDPRIGSRINGGLGTCDAHAGEDLAWVGQQTTHSGIRLVCAQRQR
HAGELRFRHANLAPHGVTQVYEGVLAPGQAVSLEKYVAYAFSSPLGGDQATDLLARARAS
LDTADALGYPALLARQARALSTLWAQADLAIDGDPTTEQALRFNLFHLFQSSSRDSHGTT
AAKGLTGEGYEGHYFWDAEVFMLPVLATLAPELARAMLLYRYRTLDHARRHARELDHPHG
ALYAWRTISGDECSSYFPSGSAQYHINAAVAWAIRLYVDASGDDAFLLAHGAEMLFETAR
IWLQIGHFSARHGGAFCIHEVTGPDEYSALVDNNHYTNRMAQRHLQDAADVADWMALSHP
AEHAALGARINLQADEASQWRRAARAMHLPVDAALGIFPQDDGFLDKPRLPPQLAATPGR
QPLLLLLHPLTLYRHQVCKQADTLLALMLAGEQVEVAAKRRNFDYYEGVTVHDSTLSAST
FAVLAAEVGYADKAHGYFLDTLRVDLDDLHGNAAHGLHMAAMAGSWLALSWGYGGLRVHD
GLPALAPRLPAAWKSYRFGLRWRGAHLRVEVDGDGARYTLTEGSSLTFLHDGLPQRLHAG
QPLHLPCAGSVAPPPLKAVVFDLDGVLADTAVLHRAAWQQLANEIGAPLDEITAGRMKGV
DRRGSLDILLEHAPRSYSETEKEALAARKNAHYIELIGRLGPQDLLPGARAAVESVRRAG
LKTALASASRNAPQLLERLGIATLFDCVVDAGRIARSKPDPEIFLAAARGLGLAPGECLG
VEDAAAGIAALHAAGMAAVGIGRAQELDQADVLLPDIAAFDISRFIA