Protein Info for LRK53_RS04910 in Rhodanobacter sp000427505 FW510-R12
Annotation: aminotransferase class III-fold pyridoxal phosphate-dependent enzyme
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
Swiss-Prot: 56% identical to AGT2L_DROME: Alanine--glyoxylate aminotransferase 2-like (CG8745) from Drosophila melanogaster
KEGG orthology group: K14286, alanine-glyoxylate aminotransferase 2-like [EC: 2.6.1.-] (inferred from 55% identity to dvi:Dvir_GJ19045)Predicted SEED Role
"aminotransferase, class III"
KEGG Metabolic Maps
- Aminophosphonate metabolism
- Arginine and proline metabolism
- Caprolactam degradation
- Lysine biosynthesis
- Lysine degradation
- Methionine metabolism
- Nucleotide sugars metabolism
Isozymes
Compare fitness of predicted isozymes for: 2.6.1.-
Use Curated BLAST to search for 2.6.1.-
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (443 amino acids)
>LRK53_RS04910 aminotransferase class III-fold pyridoxal phosphate-dependent enzyme (Rhodanobacter sp000427505 FW510-R12) MTDRAATPASGHVPARSNDEILRLRRQHLNPTLSVAYREPLKIVRGQGAWLYDQHGQGYL DMVNNVCHVGHCHPRVVAAGQAQMAQLNTNTRYLHDNIVEYALRLTATLPAPLSVVFLTN SGTEANDLALRLARAHTHARGVVVVDHAYHGHSPSMVELSPYKFNGKGGMGQSAHVGVVP MPDVYRGQLRDTPDAGRQYGQLVSPAMAELRERGVDTGVFFAESLLGCGGQILLPDGYLP AVYAAVHAAGGVCLADEVQVGFGRAGEHFWAFERQGVVPDIVTLGKPIGNGHPMGAVVTT AEIAASFVTGMEYFNTFGGNPVSCAIALAVLDVIEEEGLQENARGVGRFVMDGLRELQTR FEMIGDVRGCGLFIGAEFVSDRAARVPDAGRARAAVEAMKARRVLLSTDGPDDNVLKIKP PVVFSRSNAEEFLGKLEEVLRGL