Protein Info for LRK53_RS04655 in Rhodanobacter sp000427505 FW510-R12

Annotation: manganese efflux pump MntP family protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 188 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details transmembrane" amino acids 35 to 58 (24 residues), see Phobius details amino acids 70 to 89 (20 residues), see Phobius details amino acids 106 to 129 (24 residues), see Phobius details amino acids 134 to 158 (25 residues), see Phobius details amino acids 166 to 186 (21 residues), see Phobius details PF02659: Mntp" amino acids 31 to 182 (152 residues), 172.2 bits, see alignment E=3.4e-55

Best Hits

Swiss-Prot: 70% identical to MNTP_STRM5: Putative manganese efflux pump MntP (mntP) from Stenotrophomonas maltophilia (strain R551-3)

KEGG orthology group: None (inferred from 70% identity to smt:Smal_3977)

MetaCyc: 49% identical to Mn2+ exporter (Escherichia coli K-12 substr. MG1655)
TRANS-RXN0-487

Predicted SEED Role

"Integral membrane protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (188 amino acids)

>LRK53_RS04655 manganese efflux pump MntP family protein (Rhodanobacter sp000427505 FW510-R12)
MNPVSILLLGFAMSTDAFAAAIGKGAAMTRPRLSQAMRAGLIFGVIEAITPVIGWLLGKG
AARYIEAWDHWIAFGLLLVLGLHMIWAGVQPDSGEPVDEAKKHGIVGLAITGLSTSIDAL
AVGVGLAFVDVSIAMVAVVIGLCTFSMVTLGIMLGHVLSAMVGRRAEIIGGVILIGVGAV
ILYEHLSV