Protein Info for LRK53_RS04620 in Rhodanobacter sp000427505 FW510-R12

Annotation: CPBP family intramembrane metalloprotease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 298 transmembrane" amino acids 28 to 50 (23 residues), see Phobius details amino acids 62 to 80 (19 residues), see Phobius details amino acids 100 to 121 (22 residues), see Phobius details amino acids 133 to 154 (22 residues), see Phobius details amino acids 166 to 185 (20 residues), see Phobius details amino acids 191 to 211 (21 residues), see Phobius details amino acids 223 to 243 (21 residues), see Phobius details amino acids 261 to 283 (23 residues), see Phobius details PF02517: Rce1-like" amino acids 135 to 227 (93 residues), 75.3 bits, see alignment E=2e-25

Best Hits

Predicted SEED Role

"CAAX amino terminal protease family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (298 amino acids)

>LRK53_RS04620 CPBP family intramembrane metalloprotease (Rhodanobacter sp000427505 FW510-R12)
MHDHAIAFTTPPGAPRQRRWLLSPPGRIAIFVAWLVGLMVMLRFGFLALGMGQGTPILQQ
NLAQFVARALVPLAAYLILVKLVERRALIELAPRSLLPQGLLGALGGLLLFSAVVAVLWL
VGSYHVSAFQPHAPWLGALLVVGLGAGIGEEIVFRGVLFRIVEEGLGTWWALGISALLFG
AIHAANPGATLWSSAAIAIEAGLLFGMVYHVTRSLPVCMGLHAAWNFAQGTIYGIPVSGT
AADGWLVSTRSGPDWLTGGAFGAEASVVALALCTLGTTGLLVVARRRGSIVPPVWRRR