Protein Info for LRK53_RS04475 in Rhodanobacter sp000427505 FW510-R12

Annotation: electron transfer flavoprotein-ubiquinone oxidoreductase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 536 PF01946: Thi4" amino acids 5 to 52 (48 residues), 26.8 bits, see alignment 1.2e-09 PF00890: FAD_binding_2" amino acids 10 to 47 (38 residues), 21.4 bits, see alignment 5.3e-08 PF05834: Lycopene_cycl" amino acids 10 to 43 (34 residues), 23.8 bits, see alignment (E = 9.3e-09) PF13450: NAD_binding_8" amino acids 13 to 53 (41 residues), 27.9 bits, see alignment 9.4e-10 PF21162: ETFQO_UQ-bd" amino acids 205 to 298 (94 residues), 116.4 bits, see alignment E=2.8e-37 PF05187: Fer4_ETF_QO" amino acids 435 to 534 (100 residues), 142.6 bits, see alignment E=1.7e-45

Best Hits

KEGG orthology group: K00311, electron-transferring-flavoprotein dehydrogenase [EC: 1.5.5.1] (inferred from 81% identity to xac:XAC3575)

Predicted SEED Role

"Electron transfer flavoprotein-ubiquinone oxidoreductase (EC 1.5.5.1)" in subsystem Acetyl-CoA fermentation to Butyrate or Anaerobic respiratory reductases (EC 1.5.5.1)

Isozymes

No predicted isozymes

Use Curated BLAST to search for 1.5.5.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (536 amino acids)

>LRK53_RS04475 electron transfer flavoprotein-ubiquinone oxidoreductase (Rhodanobacter sp000427505 FW510-R12)
MSERETMEYDVVVVGAGPAGLSFAIRLKQIRPEASVCVIEKASTVGAQILSGAVIEPQPL
DALLPGWRDNPPPICVPAGEDEFWLLSKTGGRRMMVPPGMKNHGNFIVSLGAMCAWLAPQ
AEALGVDVFPGFAAADNIYNEDGSVAGVRIGDMGVAKDGSHKAGYTQGIDIKARVTVLAE
GARGSLTKQLIKRFQLDRDSDPQGYSIGIKELWQLPPGRVTPGKIVHSFGWPADTHTYGG
SFMYHLDQDRIALGYVSGLDYSDPAYQPWEAFQQWKNHPMNLPLLEGGTILSAGARAIVT
GGWQSLPKCEMPGALLIGDTAGLLNVPKVKGTHQAIRSGMLAAEHLAANGLDPAGFDAKL
RGSDAMAELKKVRNIKPAFKKGLWFGMLNAAWETVTGGLSPWTLKNKADWSSLHKLGQQE
EPRRDYVQRPLPPRDRLAGVYFAATEHDEDQPVHLHVADTDICATKCVEEYDNPCTRFCP
AAVYEMVEDTSAPHGKRLQVNAANCVHCKTCDIKDPYEIITWVTPEGGSGPNYQNL