Protein Info for LRK53_RS03500 in Rhodanobacter sp000427505 FW510-R12

Annotation: M1 family metallopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 617 signal peptide" amino acids 1 to 20 (20 residues), see Phobius details PF17900: Peptidase_M1_N" amino acids 36 to 212 (177 residues), 65 bits, see alignment E=1.5e-21 PF01433: Peptidase_M1" amino acids 246 to 437 (192 residues), 146.4 bits, see alignment E=1.5e-46 PF09127: Leuk-A4-hydro_C" amino acids 499 to 608 (110 residues), 77.5 bits, see alignment E=1.3e-25

Best Hits

KEGG orthology group: None (inferred from 55% identity to smt:Smal_3459)

Predicted SEED Role

No annotation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (617 amino acids)

>LRK53_RS03500 M1 family metallopeptidase (Rhodanobacter sp000427505 FW510-R12)
MRLLSVLALGTLVLPLAARANDPNSYAQPEQVRVTHLDLDLTIDFPRRQLDGQATLKLDW
KNPKAQSLVLDTRDLKISRVEALAADGKATPLTYALAPRDKVLGSKLTIATPKHPAQVRI
VYTSSPEASGLQWLTPAQTADKKLPFMFSQSESIHARSWVPLQDSPAIRFTYDARITAPK
DVRVVMSAINDAKHPLDGAFAFEQPHPIPSYLLAIAAGDLAVKETGPRSAVYAEPSVVNQ
AAHEFEDTEQLIAATEQLYGPYAWGRYDILVLPPSFPFGGMENPNMTFATPTVLVGDKSL
VSLVSHELAHSWSGNLVTSAAWRDIWLNEGFTTYVQGRITEAVYGKALADEEALLSARAL
QKGIGAMAANAQKLAPDPRGIGADDALSDVAYDKGSWFLRTLEQRFGREHFDAYLKGYFH
HFAFQSITTEQMLDYLKPNLIEKYPGRMGWDEVKVWVYDEGIPKDAPLPDSPRFNAIDRE
RSDFLAGSLAADKLDAKGWNTQEWMYFLDRLPDAPPLAKMQELDAAWHLTGTPNAEIGMR
WYSHAIAAGDKAVWDAAAEHMTRIGRIYLSTPLYKAFVKTPEGLAFAEQVYARAKSGYHP
LTQQVVEGIIAKAKKAK