Protein Info for LRK53_RS03155 in Rhodanobacter sp000427505 FW510-R12

Annotation: threonine synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF14821: Thr_synth_N
  • amino acids 6 to 81 (76 residues), 51.7 bits, E=8.1e-18
• PF00291: PALP
  • amino acids 85 to 385 (301 residues), 77 bits, E=1.6e-25
• TIGR00260: threonine synthase
  • amino acids 99 to 405 (307 residues), 220.9 bits, E=1.3e-69

Best Hits

KEGG orthology group: K01733, threonine synthase [EC: 4.2.3.1] (inferred from 67% identity to xal:XALc_1246)

Predicted SEED Role

"Threonine synthase (EC 4.2.3.1)" in subsystem Threonine and Homoserine Biosynthesis (EC 4.2.3.1)

MetaCyc Pathways

• aspartate superpathway (22/25 steps found)
• superpathway of L-isoleucine biosynthesis I (13/13 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis I (15/18 steps found)
• superpathway of L-threonine biosynthesis (6/6 steps found)
• superpathway of L-lysine, L-threonine and L-methionine biosynthesis II (12/15 steps found)
• L-threonine biosynthesis (2/2 steps found)

KEGG Metabolic Maps

• Glycine, serine and threonine metabolism
• Vitamin B6 metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.2.3.1

Protein Sequence (435 amino acids)

>LRK53_RS03155 threonine synthase (Rhodanobacter sp000427505 FW510-R12)
MSELLRYHSTRNAGLAVPISQAIAAGLAPDGGLYVPESLPRLDPAAFDPHGTLADTAATL
LAPFFAGDALADELPAICAEALTFDTPLRALPAHPHTAMLELFHGPTSAFKDVGARFLAA
CLRRLPRSDARPLTILVATSGDTGAAVGAAFHRQPHVRVVILYPDGLVSPRQAHQLGCFG
DNVTALRVAGRFDDCQRMVKAALNDAELQADVPLSSANSISLGRLLPQMSYYAHAALGWG
REHGTPLNFIVPTGNLGNALACLWVREMGLPVGEVRLACNANATLPEFFAGADYRPREAV
ATLANAMDVGAPSNFERLRWIFPNESALRQLLQAHSVDDATIRRTIATHAREHSEVFCPH
TATAMHLLDRLRADGDEAPWAVVATAHPAKFEGVVEPLLGHPLDLPPALAAMLARSASAE
PLAASDTALRDWLMP