Protein Info for LRK53_RS00530 in Rhodanobacter sp000427505 FW510-R12

Annotation: alpha/beta fold hydrolase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 315 transmembrane" amino acids 156 to 176 (21 residues), see Phobius details PF12146: Hydrolase_4" amino acids 38 to 189 (152 residues), 56.3 bits, see alignment E=4.6e-19 PF00561: Abhydrolase_1" amino acids 49 to 151 (103 residues), 33.7 bits, see alignment E=4.8e-12 PF12697: Abhydrolase_6" amino acids 51 to 254 (204 residues), 37 bits, see alignment E=9.3e-13

Best Hits

KEGG orthology group: None (inferred from 57% identity to bmu:Bmul_1095)

Predicted SEED Role

"Hydrolases of the alpha/beta superfamily"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (315 amino acids)

>LRK53_RS00530 alpha/beta fold hydrolase (Rhodanobacter sp000427505 FW510-R12)
MTHLMHPQTLAIHAADGYRLHARWWHRPDHADPARPVAVIAPATSVQSKYYARFAAYLFD
HGYDVVTFDYRGIGGSRYGSLRGFEAGWLDWGSDLDAVLAHVVSACPGRPVDVVGHSIGG
FLVGVAPTAARVRRIFTVGAQYAYWRDYAHWARRGMLWRWHALMPLLVALCGYLPAKRFG
WMEDTPKGVARNWSRMGPLFERSLTRHRSPGADAARLVHRFAAVTAPILALGLDDDPFGT
PAAIDRLLAYFTGAERHHLRLDAAALGFDAIGHFAFFNDRFRDALWPLALDWLRDQKITT
PPGATLTTRTGARGP