Protein Info for KEDOAH_25400 in Escherichia coli ECRC99

Name: aidA
Annotation: autotransporter outer membrane beta-barrel domain-containing protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 900 961 transmembrane" amino acids 27 to 46 (20 residues), see Phobius details PF03212: Pertactin" amino acids 494 to 615 (122 residues), 128.4 bits, see alignment E=1.5e-41 TIGR01414: outer membrane autotransporter barrel domain" amino acids 513 to 961 (449 residues), 354.5 bits, see alignment E=4.8e-110 PF03797: Autotransporter" amino acids 700 to 941 (242 residues), 134.7 bits, see alignment E=5.2e-43

Best Hits

Swiss-Prot: 96% identical to YCGV_ECOLI: Uncharacterized protein YcgV (ycgV) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 99% identity to ecy:ECSE_1251)

Predicted SEED Role

"Putative adhesion and penetration protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (961 amino acids)

>KEDOAH_25400 autotransporter outer membrane beta-barrel domain-containing protein (Escherichia coli ECRC99)
MGIKQHNGNTKADRLAELKIRSPSIQLIKFGAIGLNAILFSPLLIAADTGSQYGTNITIN
DGDRITGDTADPSGNLYGVMTPAGNTPGNINLGNDVTVNVNDASGYAKGIIIQGKNSSLT
ANRLTVDVVGQTSAIGINLIGDYTHADLGTGSTIKSNDDGIIIGHSSTLTATQFTIENSN
GIGLTINDYGTSVDLGSGSKIKTDGSTGVYIGGLNGNNANGAARFTATDLTIDVQGYSAM
GINVQKNSVVDLGTNSSIKTSGDNAHGLWSFGQVSANALTVDVTGAAANGVEVRGGTTTI
GADSHISSAQGGGLVTSGSDATINFSGTAAQRNSIFSGGSYGASAQTATAVINMQNTDIT
VDRNGSLALGLWALSGGRITGDSLAITGAAGARGIYAMTNSQIDLTSDLVIDMSTPDQMA
IATQHDDGYAASRINASGRMLINGSVLSKGGLINLDMHPGSVWTGSSLSDNVNGGKLDVA
MNNSVWNVTSNSNLDTLALSHSTVDFASHGSTAGTFTTLNVENLSGNSTFIMRADVVGEG
NGVNNKGDLLNISGSSAGNHVLAIRNQGSEATTGNEVLTVVKTTDGAASFSASSQVELGG
YLYDVRKNGTNWELYASGTVPEPTPNPEPTPAPAQPPIVNPDPTPEPDPTPNPTPTPKPT
TTADAGGNYLNVGYLLNYVENRTLMQRMGDLRNQSKDGNIWLRSYGGSLDSFASGKLSGF
DMGYSGIQFGGDKRLSDVMPLYVGLYIGSTHASPDYSGGDGTARSDYMGMYASYMAHNGF
YSDLVVKASRQKNSFHVLDSQNNGVNANGTANGLSISLEAGQRFNLTPTSYGFYIEPQTQ
LTYSHQNEMAMKASNGLNIHLNHYESLLGRASMILGYDITAGNSQLNIYVKTGAIREFSG
DTEYQLNNSREKYSFKGNGWNNGVGVSAQYNKQHTFYLEADYTQGNLFDQKQVNGGYHFS
F