Protein Info for KEDOAH_19880 in Escherichia coli ECRC99

Name: ybaQ
Annotation: HigA family addiction module antitoxin

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 131 TIGR02607: addiction module antidote protein, HigA family" amino acids 24 to 102 (79 residues), 104.3 bits, see alignment E=1.2e-34 PF01381: HTH_3" amino acids 34 to 88 (55 residues), 40.8 bits, see alignment E=9.4e-15

Best Hits

Swiss-Prot: 100% identical to YBAQ_ECOLI: Uncharacterized HTH-type transcriptional regulator YbaQ (ybaQ) from Escherichia coli (strain K12)

KEGG orthology group: None (inferred from 97% identity to sdy:SDY_0435)

Predicted SEED Role

"HigA protein (antitoxin to HigB)"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (131 amino acids)

>KEDOAH_19880 HigA family addiction module antitoxin (Escherichia coli ECRC99)
MIQYVLVSLFTGKQQLKTMKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVS
ALINNNRKLTTEMAFRLAKVFDTTVDFWLNLQAAVDLWEVENNMRTQEELGRIETVAEYL
ARREERAKKVA